临床药师参与临床Ⅰ类切口手术预防性应用抗菌药物的管理实践与效果分析  

Outcome of Clinical Pharmacists' Involvement in the Management on Prophylactic Use of Antibiotics in Patients Undergoing Type Ⅰ Incision Operations

作　　者：王惠霞[1] 滕月鹏[1] 

机构地区：[1]兰州市第二人民医院药剂科,兰州730046

出　　处：《中国医院用药评价与分析》2013年第12期1139-1142,共4页Evaluation and Analysis of Drug-use in Hospitals of China

基　　金：兰州市科技计划项目(编号:2011-2-9)

摘　　要：目的:探讨临床药师在Ⅰ类切口手术预防性应用抗菌药物的管理中发挥的积极作用与具体参与方式。方法:临床药师参与临床Ⅰ类切口手术预防性应用抗菌药物的管理,调取干预前、第1阶段干预后、第2阶段干预后外科Ⅰ类切口手术患者病历资料,进行合理性评价,并对抗菌药物预防性应用情况进行比较、分析。结果:通过药学干预,干预后Ⅰ类切口手术抗菌药物预防性使用率由干预前的97.96%下降至41.94%,总体降幅为57.19%;抗菌药物预防性应用合理率由干预前的41.91%上升至82.26%,总体升幅为96.28%;Ⅰ类切口手术患者抗菌药物费用占药品总费用的比例由干预前的47.06%降至7.78%,总体降幅为83.47%。结论:临床药师参与临床用药管理,可有效规范Ⅰ类切口手术预防性应用抗菌药物,提高用药合理性。OBJECTIVE ：To explore the clinical pharmacists＇ role in the management on prophylactic use of antibiotics for patients undergoing type I incision operations and the approaches of their involvement in the management. METHODS： Clinical pharmacists participated in the management on prophylactic use of antibiotics for patients undergoing type I incision operations and collected patients＇ medical records before and after intervention （in two stages after intervention： stage one and stage two） for evaluation of rationality and comparative analysis of the prophylactic use of antibiotics. RESULTS： Compared with before intervention, the rate of antibiotic use in patients undergoing type I incision operations decreased from 97. 96% to 41.94%, with an overall reduction of 57. 19% ; the rate of rational use of prophylactic antibiotics climbed to 82. 86% from 41.91%, with an overall increase of 96. 28% ; and the proportion of antibacterial cost in total drug cost declined from 47. 06% to 7. 78%, with an overall reduction of 83. 47%. CONCLUSION： Clinical pharmacists＇ participation in the management on clinical drug use can effectively standardize prophylactic use of antibiotics in patients undergoing type I incision operations and improve rationality in drug use.

关 键 词：临床药师 I类切口手术 抗菌药物 临床应用管理 药学干预 

分 类 号：R97[医药卫生—药品]