体外受精-胚胎移植120个妊娠周期中移植胚胎形态学分析  

Morphological analysis of transferred embryos in successful in vitro fertilization and embryo transfer treatment cycles

作　　者：徐艳文[1] 庄广伦[1] 周灿权[1] 张敏芳[1] 邓明芬[1] 

机构地区：[1]中山医科大学附属第一医院妇产科生殖医学中心,广州510080

出　　处：《中国实用妇科与产科杂志》2001年第2期95-96,共2页Chinese Journal of Practical Gynecology and Obstetrics

摘　　要：目的　为体外受精和胚胎移植临床中选择移植胚胎提供参考指标。方法　回顾性分析在本中心行IVF -ET治疗并在取卵后第 2天移植胚胎的 1 2 0个妊娠周期共 4 53个移植胚胎的资料。结果　 1 2 0个治疗周期中单胎 75例 ,双胎 33例 ,3胎 1 0例 ,4胎以及 5胎各 1例。 4细胞期胚胎所占的比例从单胎的 4 7 3%增至双胎的 53 2 %和 3胎的 72 5% ,妊娠胎数随移植胚胎中≥ 4细胞期胚胎的增多而明显增加 ( χ2 =1 0 81 3,P <0 0 5)。结论　形态学可以作为选择移植胚胎的参考指标之一 ,但如何在保证妊娠率的同时减少移植胚胎的数目而降低多胎妊娠率还需进一步的前瞻性研究。Objective To provide reliable parameter to select transferring embryos in in vitro fertilization-embryo transfer.Methods 453 embryos from 120 pregnant cycles were retrospectively analyzed.Results Among 120 pregnancies, 75 were singleton pregnancies and 45 multiple pregnancies. The ratio of 4-cell stage embryos in singleton pregnancies was 47 3%, and increased to 53 2% in twin pregnancies and 72 5% in triplet pregnancies. The more the ≥4-cell stage embryos transfered, the more the embryos implanted(P<0.05).Conclusion Morphology can be considered as a parameter to select transferring embryos, but how to determine an optimal number of embryos and decrease multiple pregnancy rate at the meantime still needs prospective study.

关 键 词：体外受精 胚胎移植 胚胎形态学 多胎妊娠 选择移植胚胎 

分 类 号：R321-33[医药卫生—人体解剖和组织胚胎学] R714.230.1[医药卫生—基础医学]