氯沙坦对充血性心力衰竭患者左心形态及功能的影响  

Effect of Losartan on echocardiographic Left heart morphology,function in patients with congestive heart failure

作　　者：焦健[1] 辛楠[2] 杨成悌[2] 余静[2] 

机构地区：[1]甘肃省人民医院心内科,甘肃兰州730000 [2]兰州医学院第二附属医院心内科,甘肃兰州730030

出　　处：《宁夏医学杂志》2001年第1期22-23,共2页Ningxia Medical Journal

摘　　要：目的　观察氯沙坦治疗充血性心力衰竭患者左心形态及功能的变化。方法　对 36例充血性心力衰竭患者在常规治疗的基础上口服氯沙坦 5 0mg/d 2～ 4周 ,治疗前后进行M型、二维、多普勒超声心动图检测。 结果　治疗前后患者左室内径 (LVD)恢复明显 (P <0 .0 1) ,左心功能指标也明显改善 (P <0 .0 1)。结论　氯沙坦对充血性心力衰竭患者血流动力学异常有明显的改善作用 。Objectives To assess effects of Losartan on echocatrdiographic left heart morphology,function in patientswith congestive heart failure(CHF).Methods 36 patients with CHF treated with oral Losartan(50mg daily)for 2～4 weeks on base of usually treated,examined by eohocaridiography.Results The results showed that Left ventricular diameter(LVD) were significantly changed(P<0.01),Letf heart function parameters were also increased significantly(P<0.01).Conclusions These results showed that Losartan in the treatment of patient with CHF is benefical on acute hamemodynamic and decreased Left ventricult diameter.

关 键 词：充血性心力衰竭 氯沙坦 超声心动图 血管紧张素Ⅱ受体拮抗剂 

分 类 号：R541.61[医药卫生—心血管疾病] R540.41[医药卫生—内科学]