经皮椎体后凸成形术对绝经后女性椎体骨折的疗效分析  

Analysis of Percutaneous Kyphoplasty on Vertebral Fractures of Postmenopausal Women

作　　者：胡戈亮[1] 明江华[1] 马永刚[1] 王钢[1] 陈庆[1] 徐格[2] 

机构地区：[1]武汉大学人民医院骨科,湖北武汉430060 [2]第三军医大学附属西南医院骨科,重庆400038

出　　处：《现代生物医学进展》2013年第35期6864-6866,共3页Progress in Modern Biomedicine

基　　金：国家自然科学基金项目(81102736);中央高校基本科研业务费专项基金科研项目(302274991)

摘　　要：目的:分析经皮椎体后凸成形术对绝经后女性椎体骨折的疗效。方法:选取68例绝经后女性椎体骨折患者并随机分为研究组和对照组,每组各34例。研究组采用经皮椎体后凸成形术(PKP)治疗,对照组采用经皮椎体成形术(PVP)治疗。分别在术前、术后1d以及术后1年对患者进行疼痛视觉类比评分(VAS),观察随访期间Cobb角的矫正程度和骨水泥渗漏情况以及相邻椎体的骨折发生率。结果:两组患者在术后各时间点VAS评分和Cobb角的矫正程度均有明显的改善(P<0.05),其中研究组术后Cobb角的矫正程度要明显优于对照组(P<0.05),同时研究组患者术后骨水泥渗漏的发生率低于对照组(P<0.05),在随访期内,对照组相邻椎体骨折的发生率高于研究组(P<0.05)。结论:PVP和PKP均能显著缓解OVCF疼痛,但是PKP比PVP更有利于矫正脊柱后凸的畸形,同时降低骨水泥渗漏和相邻椎体骨折的发生率。Objective： To analyze the clinical efficacy of percutaneous kyphoplasty on the treatment of postmenopausal women with vertebral fracture. Methods： 68 postmenopausal women with vertebral fractures were selected and randomly divided into the study group and the control group, 34 patients in each group. The patients in the study group were treated by the percutaneous kyphoplasty （PKP）, while the patients in the control group were treated by percutaneous vertebroplasty （PVP）. Then pain scores （VAS） of patients in the preoperative, postoperative for one day and one year after surgery were recorded, and the Cobb angle correction levels, bone cement leakage and adjacent vertebral fracture incidence were observed during the follow-up. Results： The postoperative VAS scores at different time and Cobb angle correction levels of patients in two groups were significantly improved （P 〈0.05）; the correction degree of postoperative Cobb angle in the study group was significantly better than that of the control group （P〈0.05）; the incidence of cement leakage rate in study group was lower than that of the control group （P〈0.05）. During the follow-up the adjacent vertebral fTacture of the control group was higher than that of the study group （P〈0.05）. Conclusion： PVP and PKP can significantly relieve pain OVCF, but PKP is better than PVP for correction ofkyphotic deformity, and decrease the rate of bone cement leakage and adjacent vertebral fractures.

关 键 词：PVP PKP 椎体骨折 

分 类 号：R68[医药卫生—骨科学]