当归补血汤治疗动脉粥样硬化的机制研究  

Study on Mechanism of Danggui Buxue Decoction in the Treatment of Atherosclerosis

作　　者：胡冠英[1] 张三印[1] 杨苗[1] 

机构地区：[1]成都中医药大学,研究生四川成都610075

出　　处：《陕西中医学院学报》2014年第1期103-105,共3页Journal of Shaanxi College of Traditional Chinese Medicine

基　　金：国家自然科学基金项目资助(81001497);四川省科技厅杰出青年学术技术带头人培育计划项目资助(2011JQ0030)

摘　　要：动脉粥样硬化(Atherosclerosis,AS)是一种慢性血管内膜损伤炎症性疾患。血管内皮细胞(VEC)、单核-巨噬细胞、T淋巴细胞、炎症介质和氧化低密度脂蛋白(ox-LDL)等对AS形成和发展起着至关重要的作用。常用于临床治疗缺血相关疾病的当归补血汤(Danggui Buxue decoction,DBD),对AS基础研究也取得了可喜进展。本文就AS病理机制、DBD治疗AS作用机制两方面展开综述,以期为DBD运用于AS的临床治疗提供理论依据,更好地为人类健康服务。Atherusclerusis （Atherosclerosis, AS） is a chronic inflammatory disease of the vascular intimal injury. Vascular endothelial cells （ VEC）, mononuclear macrophage, T lymphocyte, inflammatory mediators and oxidative low density lipoprotein （ ox - LDL） on the formation of AS and plays a crucial role in the development of. Commonly used in the clinical treatment of ischemic diseases of Danggui Buxue Decoction （ Danggui Buxue decoction, DBD）, the AS basic research has made gratifying progress. In this paper, two aspects of AS pathugenesis, treatment of DBD AS function mech anism of the review, to provide theoretical basis for clinical treatment in order to DBD to AS, better for human health.

关 键 词：当归补血汤 动脉粥样硬化 炎症介质 血液流变学 

分 类 号：R543.5[医药卫生—心血管疾病]