慢性阻塞性肺疾病凝血指标(FIB、D-D)与其冠脉造影Gensini评分相关性研究  

The study of correlation between the coagulation index( FIB、D-D) of chronic obstructive pulmonary disease and coronary angiography Gensini score

作　　者：唐永江[1] 王浩凌[1] 徐大敏[1] 徐大文[1] 

机构地区：[1]攀枝花市中心医院心内科,四川攀枝花617067

出　　处：《四川医学》2013年第9期1348-1349,共2页Sichuan Medical Journal

摘　　要：目的 观察慢性阻塞性肺疾病凝血功能变化情况.方法 选择91例COPD患者作为观察组,同期70例健康体检者作为对照组.比较两组CRP、TNF-α、IL-6、FIB、D-D水平.结果 观察组CRP、TNF-α、IL-6 FIB、D-D水平高于对照组,差异有统计学意义,P〈0.05.结论 COPD存在高凝状态,在常规治疗的同时给予合理的抗凝治疗,对有效防止血栓形成,改善患者预后有重要意义.Objective To investigate blood coagulation function in chronic obstructive pulmonary disease. Methods 91 COPD patients were regarded as the observation group, and 70 healthy cases were regarded as the control group. CRP, TNF- α, IL-6, FIB, D-D levels in the two groups were compared. Results CRP, TNF- α, IL-6, FIB, and D-D in the observation group were higher than those in the control group （ P 〈 0.05）. Conclusion COPD patients showed hypercoagulable state, clinics should give rational anticoagulant therapy in bases of conventional treatment and prevent thrombosis for improving patient prognosis.

关 键 词：慢性阻塞性肺病 炎性因子 凝血功能 

分 类 号：R563.9[医药卫生—呼吸系统]