四川地区1015例患者泌尿生殖道支原体感染的流行病学调查及抗菌药物的药敏、疗效评价  

The urogenital tract mycoplasma epidemiological of 1015 patients in Sichuan region and evaluate the efficacy of antimicrobial

作　　者：杨银忠[1] 赵鹃[1] 曾雪斌[2] 张露曦 黄灵[1] 

机构地区：[1]四川省人民医院城东病区检验科,四川成都610101 [2]四川省人民医院男科,四川成都610072 [3]成都中医药大学医学技术学院,实习生四川成都610072

出　　处：《四川医学》2013年第12期1900-1903,共4页Sichuan Medical Journal

摘　　要：目的分析四川地区1015例患者泌尿生殖道支原体感染的流行病学及部分阳性患者抗茵药物的疗效情况。方法用生物梅里埃公司试剂检测1015份临床疑似支原体感染者分泌物，判断支原体感染者并分析流行病学资料，包括感染阳性率、性别阳性率差异、季节阳性率差异、年龄组阳性率差异、不同标本来源阳性率的差异及抗茵药物的敏感性等；随访评价部分阳性者抗茵药物的疗效情况。结果1015例患者泌尿生殖道支原体感染的阳性率为53．10％；性别阳性率明显，男性阳性率为49．39％，女性阳性率为60％，差异有统计学意义（P〈0．05）；季节阳性率差异明显，第4季度阳性率（58．17％）最高，第2季度阳性率（48．36％）最低，差异有统计学意义（P〈0．05）；年龄组阳性率30“40岁组（55．52％）最高，〈18岁和〉60岁组较低，差异有统计学意义（P〈0．05）；妇科门诊阳性率（63．56％）最高，产科门诊（45．83％）较低，差异有统计学意义（P〈0．05）；原始霉素敏感性最高，环丙沙星及氧氟沙星耐药率最高；感染患者依据药敏结果用药，疾病治愈及好转率最高，经验用药疗效较差。结论四川地区泌尿生殖道支原体感染率较高，女性高于男性，秋季和30—40岁年龄是高峰组，妇科门诊中阴道炎患者感染率最高；，临床医生能够根据药敏结果选择抗茵药物可获得良好的效果。Objective To analyze the urogenital tract mycoplasma epidemiological of 1015 patients in Sichuan region and evaluate the efficacy of antimicrobial. Methods BioM6rieux production was used to detect the 1015 secretions of suspect patients and judge positive rate. The epidemiological data, including positive rate and it＇s differences in gender, seasen , age group and the source of specimen were analysised ;The efficacy of antimicrobial were evaluated by follow-up visit the infected patients. Results The positive rate was 53.10% and the infection rates in male and female patients respectively49. 39% and 60% , with statistical significance （P 〈 O. 05） ;Positive rate was significantly associated with seasons, the fourth quarter （58. 17% ） is the highest and the second quarter （48. 36% ） is the lowest, the difference was statistically significance （P 〈 0.05 ） ; in addition 30 -40 years people is the high risk group （56%） oppositely 〈 18 years and 〉60years is the lowest, the difference was statistically signifi- cance （P 〈 O. 05） ; gynecological outpatient positive rate （63.56%） is higher than obstetric outpatient （45.83）, the difference was statistically significance （P 〈 0. 05） ; pristinamycin with the most sensitivity, ciprofloxacin and ofloxacin with high resistance rates oppositely; good results were got by treatment, which based on susceptibility results of antimicrobial agents plus traditional medication. Experience treatment was less effective . Conclusion Sichuan region is a high urogenital Mycoplasma infection re- gion, higher in women than in men, winter and 30 ~ 40 year-old age group is the peak one, the vaginitis patients positive rates are highest in the gynecology clinic. Clinicians according to the results of susceptibility of antimicrobial agents can get a good result.

关 键 词：泌尿系统 生殖健康 支原体流行病 抗菌药物 

分 类 号：R691.3[医药卫生—泌尿科学]