心理干预对先兆流产患者内分泌机制的影响  

Study on influence of psychological intervention to endocrine mechanism of threatened abortion

作　　者：刘亚莉[1] 郭清皓[1] 

机构地区：[1]湖北省十堰市妇幼保健院,442000

出　　处：《中国妇幼保健》2014年第4期515-517,共3页Maternal and Child Health Care of China

基　　金：湖北省十堰市科研立项项目〔2010STT07〕

摘　　要：目的:探讨心理干预在先兆流产治疗中的临床疗效及其对内分泌的影响。方法:以先兆流产孕妇施行常规治疗+心理干预80例作为研究组,以先兆流产孕妇施行常规治疗80例作为对照组A,同期无流产病史的早孕妇女80例作为对照组B。以SCL-90症状自评量表评估心理干预对先兆流产孕妇心理状况及疗效的影响,测定各组考地松(Cortisol)、孕酮和β-hCG水平,分析其对先兆流产患者内分泌的影响。结果:先兆流产组与无流产病史组相比,SCL-90评分及Cortisol水平显著增高,孕酮和β-hCG水平显著降低(P<0.05);心理干预组与常规治疗组相比,SCL-90评分及Cortisol水平显著降低,孕酮、β-hCG水平及妊娠成功率显著增高(P<0.05)。结论:心理干预可能通过影响先兆流产患者内分泌机制发挥其治疗作用。Objective： To explore the clinical curative effect of the psychological intervention to threatenediabortion, and analyze the endocrine mechanism. Methods： 80 threatened abortion pregnant women with conventional treatment were selected as control group A, 80 patients with additional psychological intervention were selected as intervention group , 80 healthy women in early pregnancy were select- ed as control group B, then a case - control study was conducted. The SCL - 90 score and the content of cortisol, progesterone, β- hCG were tested to analyze the endocrine mechanism of psychological intervention. Results： The SCL -90 score and the content of cortisol in threatened abortion group were higher than those in healthy group, the content of progesterone and β - hCG in threatened abortion group were lower than those in healthy group. The SCL - 90 score and the content of cortisol in intervention group were lower than those in control group A, the content of progesterone , β - hCG and pregnancy rate were higher than those in control group A. Conclusion ： The psycholog- ical intervention may play an important role by affecting endocrine mechanism of threatened abortion.

关 键 词：心理干预 先兆流产 内分泌 

分 类 号：R714.21[医药卫生—妇产科学]