米非司酮联合依沙吖啶用于瘢痕子宫中期妊娠引产效果观察  

The observation of Mifepristone combined with Ethacridine used in mid-pregnancy induced labour with uterine scar

作　　者：张毅[1] 高霞[1] 周玉萍[1] 

机构地区：[1]湖北医药学院附属人民医院妇产科,湖北十堰442000

出　　处：《蚌埠医学院学报》2014年第1期66-67,共2页Journal of Bengbu Medical College

摘　　要：目的:探讨米非司酮联合依沙吖啶用于瘢痕子宫中期妊娠引产的可行性、临床效果和安全性。方法:将98例瘢痕子宫中期妊娠引产孕妇随机分为米非司酮联合依沙吖啶组(A组)和单用依沙吖啶组(B组),各49例。比较2组引产成功率、胎盘胎膜残留、宫颈裂伤发生情况。结果:A组均引产成功,B组有3例因先兆子宫破裂改行剖宫产术;2组引产成功率差异无统计学意义(P>0.05),2组孕妇宫缩发动时宫颈成熟度、胎盘胎膜残留率、宫颈裂伤率差异均有统计学意义(P<0.01),引产效果A组明显优于B组。结论:米非司酮联合依沙吖啶用于瘢痕子宫中期妊娠引产有效、安全,值得临床推广。Objective ：To investigate the feasibility, clinical effects, safety, induction of labor in mid-pregnancy patients with uterine scar treated by mifepristone combined with ethacridine. Methods：Ninety-eight mid-pregnant women with uterine scar were randomly divided into group A（ mifepristone coMbined with ethacridine） and group B（ ethacridine only） ,forty-nine cases each group. Success of induced labor, placenta fetal membrane residual rate and cervical laceration rate were observed and compared. Results：Forty-nine cases in group A were all success, 3 cases in group B were under cesarean section because of threatened uterine rupture, there were no significant difference in the success rate（P 〉 0.05）. Contractions started with cervical maturity,placenta fetal membrane residual rate, cervical laceration rate were significantly different （ P 〈 0.01 ） , the effect of induced labor, group A evidently better than group B. Conclusions： Mifepristone combined with ethacridine for mid-pregnancy abortion with uterine scar is safe, convenient, effective and worthy of clinical application.

关 键 词：药物引产 瘢痕子宫 米非司酮 依沙吖啶 

分 类 号：R719.31[医药卫生—妇产科学]