加味五福饮治疗咳嗽变异性哮喘30例临床观察  

Clinical efficacy of modified Wufu decoction in treatment of cough variant asthma:a report of 30 cases

作　　者：冯美 张建 王诚喜 

机构地区：[1]湖南省衡阳市中医医院,湖南衡阳421001

出　　处：《湖南中医杂志》2014年第1期15-17,共3页Hunan Journal of Traditional Chinese Medicine

基　　金：湖南省中医药科研计划项目(编号:2013130)

摘　　要：目的:观察加味五福饮治疗咳嗽变异性哮喘风盛挛急证的临床疗效。方法:将60例咳嗽变异性哮喘患者随机分为治疗组和对照组各30例,对照组给予西医常规治疗,治疗组在对照组治疗基础上加用加味五福饮治疗。两组均治疗8周,疗程结束后比较两组临床疗效、咳嗽症状积分、肺功能、不良反应及复发率。结果:总有效率治疗组为93.34%,对照组为76.67%,组间比较,差异有统计学意义(P<0.05);两组治疗后咳嗽症状积分及肺功能变化比较,差异均有统计学意义(P<0.05);两组均无不良反应发生,复发率治疗组为20.00%,对照组为43.30%,组内比较,差异有统计学意义(P<0.05),治疗组明显低于对照组。结论:加味五福饮治疗咳嗽变异性哮喘疗效显著,复发率低,值得临床推广应用。Objective：To observe the clinical eitlcacy of mounled Wufu decoction in the treatment of cough vari- ant asthma with syndrome of spasm in the presence of extensive wind evil. Methods ： Sixty patients with cough variant asthma were randomly divided into treatment group （ n = 30） and control group （ n = 30）. The control group received conventional Western medicine treatment,while the treatment group was given modified Wufu decoction in addition to conventional Western medicine treatment. After 8 weeks of treatment, the two groups were compared in terms of treatment outcome, cough symptom score, pulmonary function, adverse events, and recurrence rate. Results ： After treatment,the treatment group had a significantly higher overall response rate than the control group （93.33% vs 76. 67%, P 〈 0. 05 ） ;there were significant differences in cough symptom score and pulmonary function between thetwo groups（P 〈0.05 ）;no adverse events were seen in either group;the treatment group had a signiticantly lower recurrence rate than the control group （20. 00% vs 43.30%, P 〈 O. 05 ）. Conclusion：Modified Wufu decoction has significant efficacy in the treatment of cough variant asthma, and the treated patients have a low recurrence rate. It holds promise for clinical application.

关 键 词：咳嗽变异性哮喘 中西医结合疗法 加味五福饮 

分 类 号：R259.625[医药卫生—中西医结合]