心脏移植(HTx)围术期后机会性感染的治疗  

The therapy of opportunistic infection after perioperation in heart transplantation(HTx)

作　　者：彭润生[1] 王春生[1] 陈昊[1] 赖颢[1] 

机构地区：[1]复旦大学附属中山医院心外科,上海200032

出　　处：《复旦学报（医学版）》2014年第1期98-101,共4页Fudan University Journal of Medical Sciences

基　　金：上海市重点学科建设项目(B116)~~

摘　　要：目的探讨心脏移植（heart transplantion，HTx）围术期后机会性感染的常见病原体及治疗。方法对2000年5月至2012年12月间284例接受心脏移植的患者中发生围术期后机会性感染的16例临床资料进行回顾性分析。结果心脏移植围术期后感染以术后2～6个月的肺部机会性感染多见。经抗病原体有效药物治疗、积极预防继发院内感染、合理调整免疫抑制治疗、加强呼吸支持等治疗，13例治愈，3例死亡。结论心脏移植围术期后机会性感染死亡率高，早期诊断及合理有效治疗是提高治愈率的关键。Objective To investigate the opportunistic infection onset, organism and treatment after perioperation in heart transplantation （HTx）. Methods A retrospective analysis was carried out on the clinical data of 16 cases suffered from after opportunistic perioperation infection among 284 cases of HTx during May 2000 to Dec. , 2012. Results The opportunistic infection generally occurred frequently in the lung after HTx 2 to 6 months, and the organisms included virus and fungal. Sixteen patients cured and 3 died after effective antiorganism treatment, prophylaxis against nosocomial infection, modified the immunosuppressive drugs strategy and enhanced the respairation support. Conclusions Mortality was high after HTx opportunistic infection. Early diagnosis, rational and effective treatment plays an important role in improving the cure rate.

关 键 词：心脏移植(HTx) 围术期 机会性感染 

分 类 号：R654.2[医药卫生—外科学]