2型糖尿病并发脑卒中病人对富含缓释淀粉肠内营养制剂的治疗反应  

The slow release starch enteral nutrition in stroke patients with type 2 diabetes mellitus

作　　者：黎敏[1] 薛玉峰[1] 王志敏[1] 

机构地区：[1]台州市第一人民医院神经内科,浙江台州318020

出　　处：《肠外与肠内营养》2014年第1期24-26,共3页Parenteral & Enteral Nutrition

摘　　要：目的:探讨2型糖尿病并发脑卒中病人的肠内营养(EN)支持方法。方法:将50例2型糖尿病并发脑卒中的病人随机分为试验组(给予富含缓释淀粉的EN制剂瑞代)和对照组(给予普通EN制剂能全力),每组各25例。在相等热量[104.6 kJ/(kg·d)]摄入条件下,进行不同配方EN支持2周,并进行疗效比较。结果:在营养支持治疗后第14天,试验组病人空腹血糖(FBG)和餐后2 h血糖(2hBG)水平明显低于支持前和对照组(P<0.05),而糖化血红蛋白无显著改变。治疗14 d后,两组病人血清蛋白水平明显升高,与治疗前比差异有显著性统计学意义(P<0.05);试验组病人NIHSS评分亦明显高于对照组(P<0.05)。两组病人EN支持后血脂变化无显著性差异。结论:富含缓释淀粉的EN制剂能降低2型糖尿病并发脑卒中病人的血糖水平,改善临床症状和营养状况。Objective： The enteral nutrition support method was investigated in stroke patients with type 2 diabetes mellitus. Methods ： 50 cases of stroke patients with type 2 diabetes were randomly divided into slow-release starch enteral nutrition group （ruidai group, 25 cases）and normal enteral nutri- tion group （ nengquanli group,25 cases ）. In the same energy （ 104.6 kJ/kg ~ d） intake conditions, comparison of effects of different formula was made. Results ： After days 14, the fasting blood glucose （FBG） and postprandial 2 hour blood glucose（2 hBG） level in research group was significantly lower than in control group（P 〈0.05）. After 14 days, the NIHSS score of patients in experimental group was signif- icantly higher than that of the control group （ P 〈 0.05 ）. Serum protein levels between the two groups had no significant difference. Conclusion： The slow-release starch enteral nutrition （ruidai） can reduce fasting blood glucose and postprandial 2 hour blood glucose, and improve the clinical symptoms and nutri- tional status in stroke patients with type 2 diabetes mellitus.

关 键 词：脑卒中 2型糖尿病 肠内营养制剂 

分 类 号：R587.1[医药卫生—内分泌] R743[医药卫生—内科学]