药物诱导睡眠内镜检查对上气道阻塞平面形态的研究  

Research on the patterns of upper airway obstructive levels by drug-induced sleep endoscopy

作　　者：周鹏[1] 神平[1] 刘稳[1] 李培华[1] 许学谷[1] 李红权[1] 华夏[1] 

机构地区：[1]徐州医学院附属医院耳鼻咽喉头颈外科,221002

出　　处：《中华耳鼻咽喉头颈外科杂志》2014年第1期58-61,共4页Chinese Journal of Otorhinolaryngology Head and Neck Surgery

摘　　要：目的通过右美托咪定诱导睡眠内镜检查，观察阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者上气道塌陷特点。方法经多道睡眠图监测诊断为OSAHS的患者45例，右美托咪定诱导睡眠后内镜观察仰卧位患者睡眠期腭咽、口咽侧壁、舌根、会厌和喉部5个部位的塌陷情况，每个层面观察不少于3个呼吸暂停。应用ImageTool图像处理软件进行塌陷度计算，塌陷度≥75％为完全阻塞，塌陷度〈50％为无阻塞。结果45例患者中1例各平面均无完全阻塞；6例只有单平面的完全阻塞；38例存在多平面完全阻塞，其中两平面完全阻塞17例，三平面完全阻塞15例，四平面完全阻塞6例。塌陷形态：①腭咽层面有环形狭窄43例次，其中41例次完全阻塞；②口咽侧壁层面X轴方向（左右径）塌陷，完全阻塞32例次；⑧舌根呈Y轴方向（前后径）塌陷，完全阻塞和不完全阻塞分别为11例次和10例次；④会厌层面X轴方向会厌塌陷表现为卷曲折叠成“V”字型，Y轴方向塌陷受舌根后坠影响与咽后壁贴合，严重软化者如活瓣堵塞喉入口，轻度则卷曲后与塌陷的咽侧壁形成环形狭窄；⑤喉部的杓区及杓会厌襞黏膜向声门区内翻，堵塞声门。结论右美托咪定诱导睡眠内镜检查可见上气道下部阻塞呈现多样性，咽侧壁、会厌和舌根的塌陷起重要作用，并发现喉部阻塞病例。Objective To identify the patterns of airway collapse in patients with obstructive sleep apnea hypopnea syndrome （OSAHS） by dexmedetomidine induced sleep endoscopy. Methods Forty-five obstructive sleep apnea patients diagnosed by polysomnography were given dexmedetomidine intravenously. Once the patient was sedated in dorsal position, the electronic nasopharyngoscope was inserted transnasally and positioned on five levels of the upper airway sequentially （velum, oropharyngeal lateral wall, tongue base, epiglottis and larynx） to observe and document the collapse. Each level should be observed no less than three apneas. The degree of airway narrowing was calculated by using the ImageTool. No obstruction was defined when the degree of airway narrowing 〈 50%, and complete obstruction when~〉75%. Results In 45 patients with OSAHS, 1 case showed no obstruction on any level,6 cases demonstrated obstructions on single level only, and 38 cases demonstrated complete obstructions on multilevel, including 17 cases with complete obstructions on two levels, 15 cases complete obstructions on three levels, and 6 cases complete obstructions on four levels. The patterns of collapse found in the trial were： （1） circumferential stricture by velum collapse was found in 43 patients, and 41 cases showed complete obstructions; （2） the side wall of oropharynx all collapsed in a lateral configuration, and 32 cases showed complete obstructions on this level; （3）anteroposterior wallowing tongue base was common, 11 cases showed partial obstructions on level of tongue base, and 10 cases complete; （4 epiglottic collapses occurred in lateral configuration folding as V shape; in anteroposterior configuration, epiglottis met posterior wall of the pharynx due to wallowing tongue base; the server soften epiglottis obstructed the entrance of the larynx, while the mild soften epiglottis and the collapsed side wall of pharynx came into being obstructions in concentric configuration; （5）the arytenoid area and aryepiglotti

关 键 词：睡眠呼吸暂停 阻塞性 右美托咪啶 内窥镜检查 气道梗阻 

分 类 号：R766[医药卫生—耳鼻咽喉科]