苯乙烯型大孔树脂的预处理方法研究及其在中药分离纯化方面的应用  

Research on Pretreatment Method of Styrene Type Macroporous Resin and Its Application on Separation and Purification of Traditional Chinese Medicine

作　　者：吴建雄[1] 万琴[1] 秦建平[1] 王振中[1] 萧伟[1] 

机构地区：[1]江苏康缘药业股份有限公司/中药制药过程新技术国家重点实验室/江苏省企业院士工作站,江苏222001

出　　处：《世界科学技术-中医药现代化》2013年第8期1831-1836,共6页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：科学技术部国家重大新药创制项目(2011ZX09401-097):中药治疗心脑血管疾病有效成分组(群)的创新药物孵化基地;负责人:江希明

摘　　要：目的:考察苯乙烯型大孔树脂的预处理工艺及其大生产应用。方法:采用气相色谱法和原子吸收分光光度法对预处理前后的苯乙烯型大孔树脂进行有机残留和重金属进行检测,优选出预处理工艺。结果:按照优选出的预处理方法处理的苯乙烯型大孔树脂有机残留和重金属含量均符合相关规定。结论:该预处理方法简单可行,适用于大生产应用。This article was aimed to study pretreatment method of styrene type macroporous resin and its application in the industrial production. The organic residues and heavy metals of styrene type macroporous resin were detected respectively by gas chromatography and atomic absorption spectrophotometry before and after pretreatment to optimize the pretreatment process. The results showed that contents of organic residues and heavy metals of styrene type macroporous resin with the preferred method of pretreatment are in line with relevant regulations. It was concluded that this pretreatment method was simple and feasible, which is suitable to be applied in the industrial production.

关 键 词：有机残留 重金属 预处理 苯乙烯型大孔树脂 

分 类 号：R284.2[医药卫生—中药学]