紫外分光光度法测定利多卡因微乳的含量  

Determination of Lidocaine Microemulsion by UV-spectrophotometry

作　　者：曹畏[1] 周升[1] 陶涛[1] 钱玉元 王栋[1] 丁洁琼[1] 

机构地区：[1]湖北科技学院基础医学院,湖北咸宁437100

出　　处：《湖北科技学院学报（医学版）》2013年第6期469-470,共2页Journal of Hubei University of Science and Technology(Medical Sciences)

基　　金：湖北科技学院大学生课外科研课题(114)

摘　　要：目的：探讨利多卡因微乳的质量控制方法。方法采用紫外分光光度法测定其含量。结果采用紫外分光光度法测量利多卡因微乳时，在0．05～0．50mg/ml范围内线性关系良好（r＝0．9997），平均回收率为99.5％，RSD＝0．79％。结论采用紫外分光光度法测定利多卡因微乳的方法简便易行，专属性强，灵敏度高，重复性好，结果准确。Objective To explore the quality control method of lidocaine microemulsion .Methods The content of lidocaine microemulsion was determined by UV-spectrophotometry .Results The results showed that in the range of 0.05~0.50mg/ml,the linear relationship was good （r=0.9997）,the average recovery rate was 99.5%,and RSD was 0.0079.Conclusion This UV-spectrophotomey method isspecific sensitive ,reproducible and accurate for the detection of lidocaine microemulsion .

关 键 词：利多卡因微乳 紫外分光光度法 含量测定 

分 类 号：R446.5[医药卫生—诊断学]