血必净治疗支气管哮喘及其对血清血沉C反应蛋白的影响  

The clinical effects of Xuebijing treatment on bronchial asthma,serum erythrocyte sedimentation rate and C reactive protein

作　　者：林玉蓉[1] 樊淑芳[1] 

机构地区：[1]西安市北方医院呼吸科,陕西西安710043

出　　处：《西部医学》2014年第2期169-171,共3页Medical Journal of West China

摘　　要：目的观察血必净治疗支气管哮喘的效果及血清血沉、C反应蛋白的影响。方法选择西安市北方医院呼吸科2012年1月~2013年3月82例支气管哮喘患者,随机分为治疗组41例和对照组41例,治疗组给予血必净注射液50ml加甲泼尼龙40mg静脉滴注,2次/d;对照组用甲泼尼龙40mg静脉滴注,2次/d。两组患者均连续用药10天。观察患者治疗前后临床症状和肺功能情况及治疗前后血清血沉、C反应蛋白的变化。结果治疗组治疗支气管哮喘的临床有效率明显高于对照组,差异有统计学意义(P<0.05);治疗组治疗前后血清中血沉、C反应蛋白较对照组明显减少,差异有统计学意义(P<0.05)。结论血必净可以有效减少支气管哮喘患者的炎性反应,缓解支气管哮喘患者的支气管痉挛症状,减少咳嗽咳痰、喘息气急等临床症状,可以明显改善患者的肺功能。Objective To investigate the effects of Xuebijing on bronchial asthma, serum erythrocyte sedimentation rate and C reactive protein. Methods 82 patients with bronchial asthma were randomly divided into treatment group （41 patients） and control group （41 patients）. The treatment group received Xuebijing Injection 50ml plus methylprednisolo- ne 40 mg intravenous infusion, 2 times / d. The control group were treated with intravenous methylprednisolone 40 mg intravenously, 2 times / d. All patients were administered continuously for 10 days. The clinical symptoms and lung function before and after treatment serum erythrocyte sedimentation rate, C-reactive protein changes were observed. Results The clinical efficacy of treatment group was significantly higher than that of control group （P^0.05）. The ser- um erythroeyte sedimentation rate and C-reactive protein of treatment group were significantly reduced compared with that of control group （P^0.05）. Conclusion Xuebijing can effectively reduce the inflammatory response in asthma, re- lieve bronchospasm in patients with asthma symptoms, reduce cough, sputum, wheezing, shortness of breath and other symptoms, and significantly improve the patient＇s lung function.

关 键 词：血必净 甲泼尼龙 支气管哮喘 血沉 C反应蛋白 

分 类 号：R562.2[医药卫生—呼吸系统]