气相色谱法测定γ-戊内酯的方法学研究  

GC Analysis and Methodology Research for γ-Valerolactone

作　　者：王伟仙[1] 张琳[1] 刘迎新[1] 

机构地区：[1]浙江工业大学药学院,浙江杭州310032

出　　处：《浙江化工》2014年第1期40-42,共3页Zhejiang Chemical Industry

基　　金：国家自然科学基金项目(No.21106134;21276230)

摘　　要：采用内标法进行了γ-戊内酯测定的气相色谱方法学研究。采用十二烷为内标物，对气相色谱分析γ-戊内酯的专属性、精密度、准确度、检测限等进行了验证。结果表明，气相色谱检测γ-戊内酯具有良好的线性（γ-戊内酯和内标物十二烷的浓度比（g/g）在0.25～2.5之间成线性，相关系数R2=0.9984），重复测定相对标准偏差小于5.0%，加标回收率为99.5%~104.6%。实验表明内标气相色谱法可以用于γ-戊内酯的定量分析。γ -Valerolactone quantitative analysis was investigated with internal standard gas chromatography method. Using dodecane as an internal standard, the linearity of γ-valerolactone and the precision, the accuracy and the detection limit of the analysis method were studied. The results showed that the method had good linearity when the concentration ratio of γ-valerolactone and dodecane was at the range of 0.25 to 2.5. The recovery was at the range of 95.5% to 104.6% and the relative standard deviation was no more than 5%. The experiment showed that this method was feasible to γ-valerolactone quantitative analysis.

关 键 词：气相色谱法 γ-戊内酯 内标法 方法学研究 

分 类 号：O657.71[理学—分析化学] O624.5[理学—化学]