多壁碳纳米管修饰电极测定非那西汀  

Determination of phenacetin on carboxylated multiwall carbon nanotubes modified glassy carbon electrodes

作　　者：张金磊[1] 兰翠玲[1] 赵丹丹[1] 曾译葵 林小燕[1] 谭学才[2] 

机构地区：[1]百色学院化学与生命科学系,广西百色533000 [2]广西民族大学化学化工学院,广西南宁530006

出　　处：《化学研究与应用》2014年第1期28-32,共5页Chemical Research and Application

基　　金：2011年度广西教育厅项目(201103YB130)资助

摘　　要：本文研究了非那西汀在羧基化多壁碳纳米管修饰电极上的电化学行为。在0．1 mol.L-1 HAc-NaAc （pH5．3）溶液中，非那西汀在羧基化多壁碳纳米管修饰电极上有一对可逆的氧化还原峰和一个氧化峰。对各种实验条件进行了优化，测得峰电流Ip与非那西汀浓度在4．0x10-6-1．0x10-4mol.L-1范围内呈良好的线性关系，检测限为1．0x10-6mol.L-1。此修饰电极具有较好的重现性和稳定性。利用优化后的条件对尼美舒利药片进行了测定，测量值与标示值符合，回收率在96．5%-104．2%。A novel type of carboxylated multiwalled carbon nanotubes modified electrode（c-MWCNTs/GCE）was constructed and the electrochemical properties of phenacetin（PHE）were studied. In 0. 1 mol.L-1 HAc-NaAc（pH 5. 3）buffer solution,PHE exhibi-ted a couple of quasi-reversible redox peaks and an anodic peak over the potential range from 0. 2 V to 1. 2 V at c-MWCNTs/GCE. The peak current was proportional to the concentration of PHE in the range of 4. 0＆#215;10-6 to 1. 0x10-4 mol.L-1 with a detection limit of 1. 0x10-6 mol.L-1（S/N=3）. The c-MWCNTs/GCE showed excellent repeatability and stability. This method has been used to determine the content of PHE in medical tablets. The recovery was determined to be 96. 5%to 104. 2%by means of standard ad-dition method.

关 键 词：羧基化多壁碳纳米管 修饰电极 非那西汀 测定 

分 类 号：O657.1[理学—分析化学]