聚番红花红-纳米金复合膜修饰电极对鸟嘌呤的测定及应用研究  

Determination of guanine at poly( safranine T) and gold nanoparticles composite modified glassy carbon electrode and its analytical application

作　　者：牛凌梅[1] 张玉娜[2] 连靠奇[1] 石红梅[1] 徐秀娟[3] 

机构地区：[1]河北医科大学公共卫生学院,河北石家庄050017 [2]河北医科大学第四医院内分泌科,河北石家庄050011 [3]河北医科大学口腔医学院,河北石家庄050017

出　　处：《化学研究与应用》2014年第1期38-42,共5页Chemical Research and Application

基　　金：国家自然科学基金项目(81172722;81273128)资助

摘　　要：制备了聚番红花红-纳米金复合膜修饰的玻碳电极并用扫描电镜及交流阻抗进行了表征。利用差分脉冲法（ DPV）研究了鸟嘌呤在此修饰电极上的电化学行为。结果表明聚番红花红-纳米金复合膜对于鸟嘌呤的氧化能够起到明显的电催化作用。在优化条件下，鸟嘌呤的氧化峰电流与其浓度在6．0x10-7-7．0x10-5 mol.L-1范围内呈良好的线性关系，检出限为8．0x10-8 mol.L-1。该方法快速，准确，将聚番红花红-纳米金复合膜修饰电极用于实际样品的测定，结果满意。Poly（ safranine T） and gold nanoparticles composite modified glassy carbon electrode was prepared and characterised with scan electron microscope and electrochemical impedance. The electrochemical behavior of guanine at the modified electrode was studied by differential pulse voltammetry（DPV）. It was found the composite showed an obvious electrocatalytic activity for the oxi-dation of guanine. At the optimum conditions,the peak currents of guanine were proportional to the concentrations in the range of 6. 0 ＆#215; 10-7 -7. 0x10-5 mol.L-1 with the detection limits of 8. 0 x10-8 mol.L-1 . This method was rapid and accurate and the com-posite modified electrode can be applied to determine guanine in the real sample with a satisfactory result.

关 键 词：聚番红花红 纳米金 玻碳电极 鸟嘌呤 poly( safranine T) 

分 类 号：O657.1[理学—分析化学]