4-氰基-2-硝基苯甲酸甲酯的合成  

Synthesis of 4-Cyano-2-nitrobenzoate

作　　者：王聪颖[1] 高中良[1] 杨莉[1] 高雪莉[1] 时颖[1] 

机构地区：[1]河北工业大学化工学院,天津300130

出　　处：《化学试剂》2014年第2期184-186,共3页Chemical Reagents

摘　　要：以对甲苯腈为原料,经硝化、重铬酸钾/高锰酸钾氧化、酯化,得到标题化合物,产品纯度98.9%。产品结构经1HNMR验证正确。该工艺条件温和、原料易得、操作简单和成本低廉,适合工业化生产,是经济价值较高的合成路线。4-Methylbenzonitrile as the raw material, by nitra- tion, potassium dichromate/potassium permanganate oxida- tion, and esterification, the title compound with purity of 98.9% was obtained. The structure of product was confirmed by IHNMR. The process conditions aremild, easily available raw materials, simple operation, low cost, suitable for industri- al production. Thus, it is the high economic value of synthetic routes.

关 键 词：4-氰基-2-硝基苯甲酸甲酯 对甲苯腈 合成 

分 类 号：TQ460.3[化学工程—制药化工]