东莞市2008～2011年围产儿先天性心脏病监测分析  

Monitoring analysis of the perinatal congenital heart disease from 2008 to 2011 in Dongguan

作　　者：易泉英[1,2] 钟柏茂[1,2] 刘建新[1,2] 

机构地区：[1]广东省东莞市常平医院 [2]东莞市妇幼保健院,523560

出　　处：《中国妇幼保健》2014年第5期770-773,共4页Maternal and Child Health Care of China

基　　金：广东省东莞市医疗卫生科研资助重点项目目〔2012105102018〕

摘　　要：目的：了解东莞市围产儿先天性心脏病（先心病）的现状，为进一步制定先心病干预措施提供依据。方法：对2008年1月～2011年12月在东莞市各镇区住院分娩的孕满28周至产后7天的围产儿556282例进行出生缺陷监测，并对监测所得的先心病资料进行分析。结果：①4年间东莞市医院监测围产儿先心病1702例，平均发生率为3．06％e。②先心病的发生具有以下特征：孕母年龄30～35岁的先心病发生率明显高于其他各年龄组，差异有统计学意义（P〈0．01）；双胎（或多胎）妊娠先心病发生率高于单胎妊娠，差异有统计学意义（P〈0．01）；东莞市户籍孕母先心病发生率高于非东莞市户籍孕母，差异有统计学意义（P〈0．01）；男性先心病发生率高于女性，差异有统计学意义（P〈0．01）；③先心病合并其他畸形127例，占先心病的7．46％；④单一类型的先心病前3位顺位依次为：卵圆孔未闭、动脉导管未闭、房间隔缺损。结论：东莞市先心病发生率呈上升趋势，且高于全国平均水平；先心病发生率与孕母年龄、户籍、怀孕胎数、围产儿性别呈相关性；先心病的发生以单一类型为主，东莞市今后仍需进一步提高对先心病的监测水平及监测信息的准确性，降低先心病的漏报率，以获得更真实可靠的资料。Objective： To understand the current situation of the perinatal congenital heart disease in Dongguan and offer the foun- dation of how to prevent the perinatal congenital heart disease. Methods： Birth defects of 555 282 cases of perinatal which were after born 7 days and had pregnant for 28 weeks in every township in Dongguan from January 2008 to December 2011 were monitored and the data of how many babies had the perinatal congenital heart disease was analyzed. Results： （1）There were 1 702 cases of perinatal congenital heart disease in Dongguan during this four years, the average rate was 3.06%. （2）The development of the perinatal congenital heart disease had all these characteristics ： the incidence rate of the women between 30 and 35 was higher than the other ages （ P 〈 0. 01 ） ; the incidence rate of Twins or multiparty was higher than single birth （P 〈 0. 01 ） . Dongguan citizens had the higher incidence rate than that of not Dongguan citizens （ P 〈 0. 01 ） . Boys had the higher incidence rate than the girls （ P 〈 0. 01 ） . （3）There were 127 cases of having the malformation and perinatal congenital heart disease together, which occupied 7.46% of the total number of perinatal congenital heart disease. （4）The top three of the single perinatal congenital heart disease were： patent foramen ovale, patent ductus arteriosus, atrial septal defect. Conclusion： The incidence rate of congenital heart disease is increasing in Dongguan, and the incidence rate is higher than that of the national average. The inci- dence rate is relaied to the age of the pregnancy, the household registration, how many babies the woman pregnancy and the sex of the babies. Congenital heart disease mainly occurs as a single disease, Dongguan city should improve the level of monitoring the congenital heart disease and make sure the veracity of the monitoring data, decrease the rate of missing report, in order to get the more current and reliable information.

关 键 词：先天性心脏病 监测 干预 围产儿 

分 类 号：R541[医药卫生—心血管疾病]