硫酸氢钠催化合成氯乙酸异丙酯  

Catalytic Synthesis of iso-propyl Chloroacetate with Sodium Bisufate

作　　者：刘淑云[1] 俞善信[1] 

机构地区：[1]益阳师范高等专科学校化学系,湖南益阳413049

出　　处：《天津化工》2001年第1期20-21,共2页Tianjin Chemical Industry

摘　　要：硫酸氢钠能够代替硫酸用于酯化反应中。当 0 .5g一水硫酸氢钠作为催化剂 ,1 5ml环己烷为溶剂 ,由 0 .1mol氯乙酸和 0 .2mol异丙醇回流分水 2 .5h ,氯乙酸异丙酸收率可达 83%Sodium bisulfate can be used as catalyst for the esterification instead of sulphuric acid.Isopropyl chloroacetate was synthesis by 0.1 mol chloroacetic acid with 0.2 mol isopropyl alcohol,0.5 g sodium bisulfate monohydrate (NaHSO 4 ·H 2 O) as catalyst,15 ml cyclohexane as solvent,reflaxing and water segrating for 2.5 h,the yield of ester could reach 83%.

关 键 词：氯乙酸异丙酯 合成 硫酸氢钠 催化合成 

分 类 号：TQ225.3[化学工程—有机化工]