中国产藤黄属植物中抗肿瘤活性化学成分的研究概况  

Research progress of chemistry and anti-cancer activities of natural products from Chinese Garcinia plants

作　　者：付文卫[1] 谭红胜[1] 徐宏喜[1] 

机构地区：[1]上海中医药大学中药学院,上海201203

出　　处：《药学学报》2014年第2期166-174,共9页Acta Pharmaceutica Sinica

基　　金：国家自然科学基金面上项目(81173485);"085"一流学科建设科技创新支撑计划:引导创新计划(085ZY1207)

摘　　要：藤黄属(Garcinia L.)植物具有广泛的药用价值,是天然酮类、苯甲酮类等化合物的主要资源之一,这类成分具有新颖多变的结构和显著的生物活性,特别在抗肿瘤方面的研究,成为近年来天然产物的研究热点之一。本文结合作者多年来在该领域的研究工作,对中国产藤黄属植物中具有显著抗肿瘤生物活性的化学成分和生物活性的研究进展进行介绍。Garcinia plants are one of the rich sources of natural xanthones and benzophenones which have attracted a great deal of attention from the scientists in the fields of chemistry and pharmacology. Recently, many structurally unique constituents with various bioactivities, especially anti-tumor activity, have been isolated from Garcinia plants. This concise review focused on the anti-cancer activity natural products isolated from Chinese Garcinia plants, and the research finding by authors and collaborators over the past several years were cited.

关 键 词：藤黄属 化学成分 抗肿瘤活性 [口山]酮 苯甲酮 

分 类 号：R284[医药卫生—中药学]