手指末梢血检测超敏C-反应蛋白在儿童感染性疾病中应用的价值  

The value of application finger peripheral whole blood detecting hs-CRP in children infectious diseases

作　　者：陈科奇 应晟 翁凌峰 

机构地区：[1]奉化市人民医院检验科,浙江奉化315500 [2]奉化市人民医院小儿科,浙江奉化315500

出　　处：《中华医院感染学杂志》2014年第3期748-749,752,共3页Chinese Journal of Nosocomiology

基　　金：浙江省卫生厅医药卫生科技基金项目(2010KYA166)

摘　　要：目的探究儿童感染性疾病用手指末梢血检测超敏C-反应蛋白(hs-CRP)与用血浆检测的相对效果。方法随机选取2011年7月-2013年3月进行治疗的感染性疾病患儿160例,其中病毒性与细菌性感染患儿各80例,对两组患儿分别进行手指末梢全血以及血浆中hs-CRP水平检测,对检测结果采用SPSS11.0软件进行统计分析。结果细菌感染性疾病患儿的手指末梢全血及血浆中hs-CRP水平分别为(14.7±3.5)mg/L、(16.4±5.0)mg/L,明显高于病毒性感染患儿的(3.4±2.5)mg/L、(3.1±1.9)mg/L,两组之间比较差异有统计学意义(P<0.05),细菌感染组中血浆与手指末梢全血hs-CRP之间的差异无统计学意义;低、中、高值血浆与手指末梢全血hs-CRP检测结果,差异无统计学意义。结论对儿童感染性疾病患儿进行诊断时,可采用手指末梢全血代替血浆,且检测结果不会受到影响。OBJECTIVE To compare the effect between testing hs-CRP with finger peripheral whole blood and plasma in children infectious diseases. METHODS A total of 160 children were randomly selected from Jul. 2011 to Mar. 2013 in our hospital for treatment of infectious diseases, including 80 cases in viral infection and 80 cases in bacterial infections, Hs-CRP was detected with finger peripheral whole blood and plasma respectively in the two groups, and the test results were analyzed statistically, with the use of SPSS11. 0 software. RESULTS The hs-CRP levels in whole blood and plasma were （14. 7± 3. 5）mg/L, （16. 4± 5. 0） mg/L to the patients with bacterial infections, which were obviously higher than patients with viral infections （3.4± 2.5） mg/L, （3. 1 ±1.9） mg/L, and the differences between the two groups was statistically significant （P〈 0. 05）, while the different levels of hs-CRP in plasma and whole blood was not statistically significant. In low, medium and high groups, the testing results of hs-CRP in plasma and whole blood had no statistically significant differences. CONCLUSION Patients with infectious diseases in children can be diagnosed with a finger peripheral whole blood instead of plasma, and the test results are not affected.

关 键 词：手指末梢血 超敏C-反应蛋白 儿童 感染性疾病 

分 类 号：R446[医药卫生—诊断学]