Effects of internal noise on the spiking regularity of a clustered Hodgkin–Huxley neuronal network  

作　　者：Xiaojuan Sun 

机构地区：[1]School of Science, Beijing University of Posts and Telecommunications

出　　处：《Theoretical & Applied Mechanics Letters》2014年第1期35-40,共6页力学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(11102094 and 11272024);the Fundamental Research Funds for the Central University(2013RC0904)

摘　　要：Spiking regularity in a clustered Hodgkin–Huxley（HH） neuronal network has been studied in this letter. A stochastic HH neuronal model with channel blocks has been applied as local neuronal model. Effects of the internal channel noise on the spiking regularity are discussed by changing the membrane patch size. We find that when there is no channel blocks in potassium channels, there exist some intermediate membrane patch sizes at which the spiking regularity could reach to a higher level. Spiking regularity increases with the membrane patch size when sodium channels are not blocked. Namely, depending on different channel blocking states, internal channel noise tuned by membrane patch size could have different influence on the spiking regularity of neuronal networks.Spiking regularity in a clustered Hodgkin–Huxley（HH） neuronal network has been studied in this letter. A stochastic HH neuronal model with channel blocks has been applied as local neuronal model. Effects of the internal channel noise on the spiking regularity are discussed by changing the membrane patch size. We find that when there is no channel blocks in potassium channels, there exist some intermediate membrane patch sizes at which the spiking regularity could reach to a higher level. Spiking regularity increases with the membrane patch size when sodium channels are not blocked. Namely, depending on different channel blocking states, internal channel noise tuned by membrane patch size could have different influence on the spiking regularity of neuronal networks.

关 键 词：spiking regularity internal noise clustered neuronal network Hodgkin–Huxley neuron 

分 类 号：TN911.4[电子电信—通信与信息系统]