气相色谱法测定苦参苍术口服液中三氯甲烷残留量  

Determination of Chloroform Residue in Kushencangzhu Oral Liquid by Gas Chromatography

作　　者：范强[1] 刘自扬[1] 万仁玲[1] 段文龙[1] 

机构地区：[1]中国兽医药品监察所,北京100081

出　　处：《中国兽药杂志》2014年第2期31-33,共3页Chinese Journal of Veterinary Drug

基　　金："十一五"国家科技支撑计划"中兽药现代化技术研究与开发"(2008BADB4B04)

摘　　要：建立了苦参苍术口服液中三氯甲烷残留量的气相色谱检测方法，采用DB—FFAP毛细管柱，柱温为程序升温，氢火焰离子化检测器（FID），检测器温度为250℃，进样口温度为220oC，载气为氮气。试验结果三氯甲烷在6．0464～120．928μg／mL浓度范围内呈良好的线性关系（r=0．99995），加样回收实验平均回收率为98．01％（RSD=1．6％）。本方法简便、快速、准确、重现性好，可作为苦参苍术口服液中三氯甲烷残留量的检测方法。Abstract： To establish a gas chromatography method for the determination of chloroform residue in Kushencangzhu oral liquid. Chloroform was determined on DB-FFAP capillary column using temperature programming. FID was used as detector with a temperature of 250 ℃, and the temperature of sample injection was 220 ℃, nitrogen was used as carrier gas. The linear range of chloroform was 6.0464-120.928 μg/mL（ r = 0.99995）. The average recovery was 98.1% （ RSD = 1.6%）. The method is simple, fast, accurate and reproducible, it can be used for the determination of residual chloroform in Kushenangzhu oral liquid.

关 键 词：气相色谱法 苦参苍术口服液 三氯甲烷 

分 类 号：S853.73[农业科学—临床兽医学]