Effects of nanoparticles on devitrification and recrystallization of aqueous glycerol and PEG-600 solutions  

作　　者：LV FuKou LIU BaoLin LI WeiJie SONG XiaoYan 

机构地区：[1]Institute of Biothermal Science and Technology, University of Shanghai for Science and Technology

出　　处：《Science China(Technological Sciences)》2014年第2期264-269,共6页中国科学（技术科学英文版）

基　　金：supported by the National Natural Science Foundation of China(Grant No.51076108);the Doctoral Program(Grant No.20103120110005);the Shanghai Dongfang Scholars Program

摘　　要：Nanoparticles in solution offer unique electrical, mechanical and thermal properties due to their physical presence and interac- tion with the state of dispersion. This work is aimed to study the effects of hydroxyapatite （HA） nanoparticles on the behavior of devitrification and recrystallization of glycerol （60% w/w） and PEG-600 （50% w/w） solutions during warming. HA nano- particles of different sizes （20, 40, 60 nm） and concentrations （0.1%, 0.5%, w/w） were incorporated into solutions, and were studied by calorimetric analysis coupled with cryomicroscopy. The presence of HA nanoparticles has little effect on the devit- rification end temperatures, but affects the devitrification onset temperatures of glycerol and PEG-600 solutions. The investi- gation with the cryomicroscope observed that the ice morphologies of glycerol and PEG-600 solutions are dendritic and spher- ic respectively. The ice fraction of glycerol solution containing 0.1% HA with the size of 60 nm decreased to 2/5 of that of the solution without nanoparticles at -45℃. The ice fractions of PEG-600 solutions increased signifcantly between -64℃ and -54℃, and the ice fraction of PEG-600 solution without nanoparticles increased by 92% within the temperature range. The findings have significant implications for biomaterial cryopreservation, cryosurgery, and food manufacturing. The complexity of ice crystal growth kinetics in nanoparticle-containing solutions awaits further study.

关 键 词：NANOPARTICLES DEVITRIFICATION RECRYSTALLIZATION ice morphology ice fraction 

分 类 号：TB383.1[一般工业技术—材料科学与工程]