小干扰RNA非病毒载体研究进展  

The Research of Non-viral Small Interfering RNA Delivery Carriers

作　　者：龚建勇[1] 

机构地区：[1]海军上海保障基地医院药剂科,上海200083

出　　处：《药品评价》2013年第24期6-9,19,共5页Drug Evaluation

摘　　要：作为一种新的基因治疗方法,小干扰RNA(small interfering RNA,siRNA)载体技术的发展,对许多疾病的临床治疗起着至关重要的作用。本文根据近年来国内外文献报道,将siRNA非病毒纳米载体研究进展进行了综述,并分析了现阶段存在的问题,展望了今后的发展方向。As a new genic therapy method, development of small interfering RNA （siRNA） delivery vehicles is very important for clinical treatment of many diseases. According to the domestic and abroad literatures in recent years, studies of non-viral nanoparticle of siRNA were reviewed. At the same time, the issues existing in present stage and future development were discussed.

关 键 词：纳米粒 非病毒递送载体 研究进展 

分 类 号：R450[医药卫生—治疗学]