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作 者:梁一鸣[1]
出 处:《国际医药卫生导报》2014年第3期358-360,共3页International Medicine and Health Guidance News
摘 要:目的 探讨血液透析滤过对血液透析患者微炎症状态的影响作用.方法 选取血液透析室维持性血液透析(maintenance hemodialysis,MHD)患者30例,随机分为观察组和对照组各15例.观察组采取血液透析联合血液透析滤过治疗,对照组采取血液透析治疗,观察并记录两组ALb、BUN、Scr、IL-6、TNF-α、hs-CRP的改善情况.结果 观察组患者透析12周后TNF-α、IL-6、hs-CRP均显著低于对照组,Alb则显著升高,两组比较差异均有统计学意义(P<0.05).结论 MHD患者采取血液透析滤过治疗,能够很好的改善患者的微炎症状态,提高患者生存质量.Objective To study the hemodialysis filtration effect on the inflammatory state of hemodialysis patients.Methods We selected 30 cases of maintenance hemodialysis (MHD) patients in hemodialysis room,and randomly divided them into observation group and control group (n=15).Observation group was treated with hemodialysis combined with hemodialysis filtration,the control group was treated with hemodialysis,then observed and recorded the improvement conditions of ALb,BUN,Scr,IL-6,TNF alpha and hs-CRP levels in two groups.Results 12 weeks after treatment IL-6,TNF alpha,hs-CRP levels in observation group patients were significantly lower than those in the control group,ALb propagated level was higher,the comparative differences showed statistical significance (P < 0.05).Conclusion Hemodialysis filtration in treatment for MHD patients can effectively improve the patients' micro inflammatory state,and improve their quality of survival.
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