支气管激发试验在慢性咳嗽诊断中的应用  

Diagnostic Value of Bronchial Provocation Test for Chronic Cough

作　　者：李光清[1] 吴昭萍[1] 李小波[1] 徐登城[1] 亓占中[1] 梁颖隽[1] 许燕[1] 李少红[1] 唐文艳[1] 

机构地区：[1]解放军第452医院呼吸内科,成都610041

出　　处：《中国循证医学杂志》2014年第2期162-164,共3页Chinese Journal of Evidence-based Medicine

基　　金：四川省科技厅科技支撑计划(编号:2011SZ0140)

摘　　要：目的探讨支气管激发试验在慢性咳嗽诊断中的应用价值。方法对2011年3月至2012年2月就诊于解放军第452医院的550例慢性咳嗽患者行基础肺功能和乙酰胆碱支气管激发试验,检测其气道高反应性,并评价支气管激发试验在诊断慢性咳嗽中的价值。结果所有受检者肺功能均正常,其中支气管激发试验阳性者267例,占48.5%;该267例受检者中,236例最终诊断为咳嗽变异性哮喘,经正规治疗后咳嗽得到有效控制。结论咳嗽变异性哮喘是慢性咳嗽的主要病因之一,支气管激发试验是协助诊断咳嗽变异性哮喘的重要方法,有助于早期明确诊断。Objective To investigate the diagnostic value of bronchial provocation test in patients with chronic cough. Methods A total of 550 chronic cough patients were selected in the 452nd Military Hospital from March 2011 to February 2012. These patients all underwent the basic lung function test and the bronchial provocation test （BPT） to acetylcholine so as to assess the bronchial hyper-reactivity by inhaling methacholine. The diagnostic value of BPT was then evaluated. Results All included patients had normal lung function. There were 267 patients （48.5%） who showed positive results in BPT, of whom, 236 BPT-positive patients were finally diagnosed as cough variant asthma. After regular treatment, the cough symptoms were well controlled. Conclusion Cough variant asthma is one of the main causes of chronic cough. The BPT is an important method of aiding the diagnosis of cough variant asthma which helps early diagnosis of it.

关 键 词：慢性咳嗽 支气管激发试验 咳嗽变异性哮喘 

分 类 号：R56[医药卫生—呼吸系统]