异丙酚复合氯胺酮静脉麻醉应用于小儿扁桃体切除术  

Propofol-Ketamine Compound Used for Transvenous Anaesthesia in Children's Tonsillectomy

作　　者：祝力群 胡凤蕴 张世峰 

机构地区：[1]山东省枣庄矿业集团公司中心医院,277011

出　　处：《医学理论与实践》2001年第2期114-115,共2页The Journal of Medical Theory and Practice

摘　　要：目的:观察异丙酚复合氯胺酮静脉麻醉用于小儿扁桃体切除术的效果,并与氯胺酮与羟丁酸钠复合进行对比。方法:择期手术患者48例,随机分为实验组(n=24),对照组(n=24)。异丙酚诱导剂量为2mg/kg,维持4mg·kg^(-1)·h^(-1),氯胺酮诱导剂量2mg/kg,连续监测MAP,HR及sPO_2,记录起效时间和清醒时间。结果:实验组起效时间和清醒时间明显短于对照组(P<0.01),两组均有sPO_2下降,无统计学差异(P>0.05)。结论:在小儿扁桃体切除术中应用异丙酚复合氯胺酮静脉麻醉是较好的麻醉选择。Objective:To observe the effect of propofol-ketamine used for transvenous anaesthesia in children's tonsillectomy and compare it with ketamine-r-hydroxybutyrate sodium in anaesthesia effect. Methods : 48 cases were divided into experimental group (propofol-ketamine)(n =24) and control group (ketamine-y-hydroxybutyrate sodium)(n =24) randomly. The propofol dose for anaesthesia induction was 2 mg/kg and the dose for maintenance was 4mg·kg-1·h-1 ,and the ketamine dose was 2mg/kg. MAP, HR and sPO2 were continuably and the times of ouset and recovery were recorded. Results: The times of ouset and recovery in experimental group were shorter than that in control group (P<0.01). sPO2 was reduced in both groups, and there was no difference in statistics (P > 0.05). Conclusion: The propofol-ketamine compound is better than ketamine-γ-hydroxybutyratesodium compound for transvenous anaesthesia in children's tonsillectomy.

关 键 词：异丙酚 氯氨酮 麻醉 扁桃体切除术 儿童 

分 类 号：R767.91[医药卫生—耳鼻咽喉科] R614[医药卫生—临床医学]