亚低温联合IABP治疗心脏外科术后低心排的效果研究  

Evaluation of the Effectiveness of Mild Hypothermia and IABP in Postcardiac Surgical Patients with Severe Heart Failure

作　　者：赵晓琪[1] 谷天祥[2] 钱程[2] 

机构地区：[1]中国医科大学附属第一医院心脏外科科,辽宁省沈阳市110001 [2]中国医科大学附属第一医院心脏外科,辽宁省沈阳市110001

出　　处：《天津医药》2014年第2期141-142,共2页Tianjin Medical Journal

基　　金：辽宁省科技计划项目(项目编号:2009225010-14)

摘　　要：目的探讨亚低温联合主动脉球囊反搏(IABP)治疗心脏外科术后低心排的临床效果。方法选取因心脏外科术后应用大剂量血管活性药物但未改善低心排,而采取IABP及亚低温联合治疗的患者12例。监测患者在联合治疗前后心脏指数(CI)值、混合静脉血氧饱和度(SvO2)、尿量及肌酐(Cr)的变化。结果亚低温联合IABP治疗后,患者CI较治疗前明显改善[L/(min·m2):2.4±0.5 vs 1.6±0.2)],SvO2升高(0.65±0.07 vs 0.52±0.05)。尿量明显增加[mL/(kg·h):2.9±1.9 vs 1.2±0.9],Cr明显下降(mmol/L:95±10 vs 282±25)。结论亚低温联合IABP治疗心脏外科术后低心排能有效改善循环功能,且操作简单易行。Objective To evaluate the effectiveness of mild hypothermia and the intra-aortic balloon pump （IABP） in postcardiac surgical patients with severe heart failure. Methods Twelve patients took combination therapy of IABP and mild hypothermia after cardiac surgery, which did not improve the low cardiac output with massive doses of catecholamine, were included in this study. The values of cardiac index （CI）, mixed venous oxygen saturation （SvO2）, urine volume and creati-nine （Cr） were measured before and after treatment. Results After combination therapy of IABP and mild hypothermia, the value of CI was improved obviously [L/（min±183;m2）：2.4±177;0.5 vs 1.6±177;0.2], the value of SvO2 increased （0.65±177;0.07 vs 0.52±177;0.05 ）, urine output increased obviously [mL/（kg±183;h）：2.9±177;1.9 vs 1.2±177;0.9 ] and the value of Cr decreased obviously （mmol/L：95±177;10 vs 282±177;25 ）. Conclusion The combination therapy of mild hypothermia and IABP is an effective and simple procedure for the postcardiac surgical patients with severe heart failure.

关 键 词：主动脉球囊反搏 亚低温 心脏外科 心排血量 低 心脏指数 血氧饱和度 尿量 肌酐 

分 类 号：R654.2[医药卫生—外科学]