代谢综合征与精神性疾病共病的研究进展  

The Advance of Comorbidity of Metabolic Syndrome and Psychiatric Disease

作　　者：雒瑢[1] 刘新轶[2] 田凤石[3] 

机构地区：[1]天津市胸科医院内分泌科,300051 [2]天津市公安局安康医院临床八科 [3]天津市第四中心医院

出　　处：《天津医药》2014年第2期188-191,共4页Tianjin Medical Journal

摘　　要：代谢综合征和精神性疾病相继或伴随发生的现象已日益普遍,临床上称之为共病。流行病学调查显示,精神分裂症和心境障碍是最常见的与代谢综合征共同存在的精神性疾病。精神性疾病与代谢综合征共病的发病机制与下丘脑-垂体轴功能紊乱、不良生活方式和抗精神病药物的应用有关,精神分裂症与代谢综合征伴发的一个重要原因是遗传,而心境障碍和代谢综合征联系的关键因素之一则是炎症。在精神性疾病与代谢综合征共病的诊疗方案中,生活方式干预、心理疏导和合理的药物选择缺一不可。对精神性疾病患者代谢指标的监测和代谢综合征患者心理状况的关注应贯穿于这两大类疾病诊治的全过程之中。The frequent co-occurrence of metabolic syndrome （MS） and mental disorders has become increasingly common, which is known clinically as comorbidity. Epidemiological survey showed that schizophrenia and mood disorders are the most common co-existing psychiatric disorders of metabolic syndrome. The pathogenesis of comorbidity of mental dis- orders and MS is related with hypothalamic-pituitary-adrenal axis dysfunction, unhealthy lifestyles and related applications of antipsychotics. An important reason for the metabolic syndrome associated with schizophrenia is heredity. However, in- flammation is the key factor in the relationship of mood disorders and MS. The intervention of unhealthy lifestyle, psychologi- cal counseling and rational use of drug should all be included in the treatment of comorbidity of psychiatric disorders and MS. The follow-up of metabolic index in psychiatric patients and psychological conditions in patients of MS should be paid more attention during the whale course of treatment.

关 键 词：代谢综合征X 共病现象 精神分裂症 情绪障碍 行为障碍 综述 

分 类 号：R589[医药卫生—内分泌]