肺动脉高压相关因子的研究进展  

Research Progress of Factors Related with Pulmonary Arterial Hypertension

作　　者：王鹏[1] 赵延恕[1] 

机构地区：[1]中南大学湘雅二医院心内科,长沙410011

出　　处：《医学综述》2014年第3期408-411,共4页Medical Recapitulate

摘　　要：肺动脉高压(PAH)是一组由异源性疾病和不同发病机制引起的以肺血管阻力持续增加为特征的临床病理生理综合征,其病理变化包括肺血管收缩、细胞增殖、体内血栓形成,发病机制极为复杂,许多环节仍然不明确,有待于深入研究。近年来有关PAH及相关因子方面的研究已成为国内外学术热点,该文通过总结PAH最新研究,以提供临床和基础医学研究的新观点。Pulmonary arterial hypertension is a clinical-pathological physiological syndrome characterized by persistent excessive vascular resistance and caused by heterologous diseases and different pathogenesis. Its pathological changes include pulmonary vasoconstriction, cell proliferation, and thrombosis. The pathogenesis is extremely complex, and many aspects are still not clear and need in-depth study. In recent years, research on PAH and related factors at home and abroad has become academic hot issue, and here is to summarize the latest research on PAH and provide new points of view of the clinical and basic medical research.

关 键 词：肺动脉高压 血管收缩 血管重构 

分 类 号：R543.2[医药卫生—心血管疾病]