特发性肺纤维化病因学的新进展  

New Progress in Idiopathic Pulmonary Fibrosis Etiology

作　　者：王小华[1] 段军[1] 

机构地区：[1]新疆医科大学第五附属医院职业病防治科,乌鲁木齐830011

出　　处：《医学综述》2014年第3期414-416,共3页Medical Recapitulate

摘　　要：特发性肺纤维化(IPF)也称为隐进展性纤维肺泡炎,是特发性肺炎家族的一员,其临床特点为气短、明显的弥漫性肺部浸润和不同程度的炎症、纤维化。IPF的发展受遗传因素和环境因素的共同影响。其中环境因素包括细菌、病毒感染,吸烟、药物、木尘或金属粉尘等,连接个体暴露在环境中的遗传易患性。该文首先简单地介绍IPF,其次总结遗传和环境因素对肺纤维化的相关影响,为IPF提供更好的预防和治疗方案。Idiopathic pulmonary fibrosis （IPF） , also known as cryptogenic fibrosing aleolitis, is a member of idiopathic pneumonias family with the clinical features of shortness of breath, evident diffuse pulmonary infiltrates, and varying degrees of inflammation and fibrosis. Development of IPF is influenced by both genetic and environmental factors. Environmental factors include bacteria and virus infection, smoking, drugs, wood dust or metal dust,etc. Here is to make a review of PIF,followed by brief summaries of genetic and environmental factors relevant to IPF,to provide the prevention and treatment of IPF.

关 键 词：肺纤维化 遗传因素 环境因素 

分 类 号：R563.9[医药卫生—呼吸系统]