A fat story--antigen presentation by butyrophilin 3A1 to γδ T cells  

A fat story--antigen presentation by butyrophilin 3A1 to γδ T cells

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作  者:Charlotte Esser 

机构地区:[1]Molecular Immunology, IUF--Leibniz ResearchInstitute for Environmental Medicine, DOsseldorf,Germany

出  处:《Cellular & Molecular Immunology》2014年第1期5-7,共3页中国免疫学杂志(英文版)

摘  要:Antigen specificity and receptor diversity are hallmarks of B and T cells. Only 1%-5% of all T cells bear a γδ T-cell receptor (TCR), and these cells have features of both innate and adaptive cells. While the antigen presentation process was long ago elucidated for αβ T cells, it has remained enigmatic for γδ T cells. In a recent study by Vavassori and co-workers,1 this major gap in know-ledge was addressed and dosed.Antigen specificity and receptor diversity are hallmarks of B and T cells. Only 1%-5% of all T cells bear a γδ T-cell receptor (TCR), and these cells have features of both innate and adaptive cells. While the antigen presentation process was long ago elucidated for αβ T cells, it has remained enigmatic for γδ T cells. In a recent study by Vavassori and co-workers,1 this major gap in know-ledge was addressed and dosed.

关 键 词:T细胞 抗原提呈 脂蛋白 故事 AE 细胞受体 抗原特异性 抗原递呈 

分 类 号:S858.31[农业科学—临床兽医学] S852.4[农业科学—兽医学]

 

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