在成年吸烟人群中联合应用无创血管功能状态检测方法的意义  

Combined application value of non-invasive detection methods of vascular function and status among adult smokers

作　　者：陈桂英[1] 郭来敬[2] 廖燕华[1] 梁娜[1] 邢敏[1] 谢艳[1] 

机构地区：[1]北京大学首钢医院古城社区卫生服务中心,北京100041 [2]北京大学首钢医院慢病研究所

出　　处：《中国冶金工业医学杂志》2014年第1期1-3,共3页Chinese Medical Journal of Metallurgical industry

摘　　要：目的探讨在成年吸烟人群中联合应用无创血管功能状态检测方法的价值。方法对北京市石景山区古城社区18岁以上常住居民2739例进行调查随访,调查指标包括烟龄、男女吸烟比例等,同时对脉搏波传导速度(PWV)、踝臂指数(ABI)以及颈动脉斑块等指标进行测定。结果 2739例受访对象中男952例,女1787例,吸烟组462例,吸烟率为16.9%(462/2739);吸烟组中男417例,吸烟率为43.8%(417/952),女45例,吸烟率为2.5%(45/1787),男性明显多于女性,差异有统计学意义(P<0.01)。吸烟组颈动脉内中膜厚度(IMT)增厚、斑块形成及狭窄均与不吸烟组比较差异有统计学意义(P<0.01);PWV两组差异无统计学意义(P>0.05);而ABI吸烟组与不吸烟组差异有统计学意义(P<0.05)。吸烟与颈动脉内膜增厚、颈动脉斑块及狭窄的相关性分析均呈正相关(P<0.01),与ABI呈负相关(P<0.01),与PWV不相关。结论吸烟是颈动脉硬化改变的独立危险因素,因此,在吸烟人群中,尽早联合进行PWV、ABI以及颈动脉IMT等指标检查,可能对于早期预防和治疗动脉粥样硬化具有更重要的意义。Objective To explore combined application value of non-invasive detection methods of vascular function and status among adult smokers. Methods A total of 2739 people over 18 years who were residents from Shijingshan District of Beijing were involved in the follow-up survey. The smoking history and proportion of male and female were taken as investigation indicators. PWV and ABI as well as carotid artery were determined. Results Among 2739 participants,952 were males and 1787 females. The smoker group included 462 smokers with a smoking rate of 16.9%. In the smoker group,there were 417 males with a smoking rate of 43.8% and 45 females with a smoking rate of 2. 5%. There were more males than females（P〈0.01）. The detection rate of carotid IMT thickening,plaque formation and stenosis was higher in the smoker group than in non-smoking group. There was no difference in the PWV of two groups（P 〉0.05）, while there was difference in the ABI of two groups （P 〈 0. 05）. Correlation analysis showed it was a positive correlation in smoking with carotid intimal thickening,carotid artery plaque and carotid artery stenosis（P 〈0.01）, after controlling for other risk factors partial correlation analysis was still a positive correlation （P 〈 0.01 ）. There was a negative correlation in smoking with ABI（P〈0. 01） ,and an irrelevant between smoking and PWV. Conclusion Smoking was an independent risk factors of carotid atherosclerosis change, therefore,it might be a more important significance for early prevention and treatment of atherosclerosis among smokers,early combined detect PWV, ABI and carotid indicators examination.

关 键 词：吸烟 脉搏波传导速度 颈动脉斑块 踝臂指数 

分 类 号：R543[医药卫生—心血管疾病]