补肾疏肝汤加味治疗失眠的疗效观察  

Observation on Therapeutic Effect of Bushen Shugan Decoction in Treatment of Insomnia

作　　者：牛占忠[1] 张喜平[1] 杜杏坤[1] 陈宝财[1] 

机构地区：[1]沧州医学高等专科学校,河北沧州061000

出　　处：《辽宁中医杂志》2014年第2期281-283,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：沧州市科学技术研究与发展指导计划项目(1123079ZD)

摘　　要：目的:通过运用中药补肾疏肝汤加味和氯硝安定治疗失眠的疗效对比,以探讨中药补肾疏肝汤治疗失眠的效果。方法:将符合实验入组标准的96例失眠患者随机分成两组:治疗组和对照组,其中治疗组运用中药补肾疏肝汤治疗,对照组运用氯硝安定治疗,疗程为30天。疗程结束后对两组进行疗效观察。结果:两组患者治疗后的有效率分别为:治疗组91.7%,对照组83.4%,两组比较有显著性差异(P<0.05)。治疗结束10天后回访有效率分别为:治疗组77.1%,对照组,39.6%,两组比较有显著性差异(P<0.01)。两组患者治疗结束10天后回访匹兹堡睡眠质量指数(PSQI)评分比较:治疗组为(6.64±1.58)分,对照组为(11.92±2.13)分,两组对比有显著性差异(P<0.01)。且对照组患者的药物副反应明显高于治疗组。结论:中药补肾疏肝汤加味对失眠患者有显著的治疗作用,且其疗效优于氯硝安定,尤其远期疗效更优于氯硝安定。Objective：To study the efficacy of Bushen Shugan Decoction in treatment of insomnia by comparing with Clonaze- pare. Methods ：96 eases were divided into 2 groups randomly： treated group with Bushen Shugan Decoction and control group with Clonazepam. Both groups were observed after 30 days. Results ：Treatment group＇s clinical total effectiveness was 91.7% ,and that of the control group was 83.4%. The comparison differences had statistics significance （P 〈 0.05 ）. 10 days after the treatment finished, the treatment group＇s clinical total effectiveness was 77.1%, and that of the control group was 39.6%. The comparison differences had statistics significance（P 〈 0.01 ）. The scores of PSQI of the treatment group was 6.64 ± 1.58, and the control group＇s was 11.92 ± 2.13. The comparison differences had statistics significance （P 〈 0.01 ）. At the same time, the adverse reac- tions of control group were more serious than that of the treatment group. Conclusion：The efficacy of Bushen Shugan Decoction in treatment of insomnia is more remarkable than Clonazepam, especially the long - term efficacy.

关 键 词：失眠 中药治疗 补肾疏肝汤 

分 类 号：R256.23[医药卫生—中医内科学]