光诱导α-氨基酸的脱羧加成反应  

Decarboxylation Addition Reaction of α-amino Acid by Photochemistry

作　　者：石志芳[1] 张荣华[1] 

机构地区：[1]同济大学化学系,上海200092

出　　处：《广东化工》2014年第4期1-2,共2页Guangdong Chemical Industry

摘　　要：文章主要研究以α-氨基酸和缺电子烯烃作为反应底物的Michael加成反应,以乙腈作溶剂,菲(phen)、1,4-二氰基萘(DCN),1,4-二氰基苯作光敏剂,在紫外光的照射下通过单电子转移过程,与缺电子烯烃发生加成反应,形成一系列脱羧加成产物。该类反应条件温和,产物的产率达65%。This paper mainly research Michael addition reaction, which use amino acid and electron deficient alkenes as reaction substrates. With acetonitrile as the solvent, with phenanthrene, 1,4-dicyanonaphthalene, 1,4-dicyanobenzyl as photosensitizer, with the irradiation of ultraviolet light to tbnn a series of decarboxylation addition products. The reaction condition is mild and the yield of the product is 65 %.

关 键 词：有机光化学 脱羧 缺电子烯烃 自由基加成 

分 类 号：O621.3[理学—有机化学]