体外反搏联合丹红注射液治疗不稳定型心绞痛的临床疗效  

Therapeutic effect of external counterpulsation combined Danhong injection on unstable angina pectoris

作　　者：于华[1] 安毅[2] 

机构地区：[1]青岛大学医学院附属心血管病医院心内科,山东青岛266071 [2]青岛大学医学院附属医院

出　　处：《心血管康复医学杂志》2014年第1期78-82,共5页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:观察体外反搏联合丹红注射液对不稳定型心绞痛患者的治疗效果。方法:选择183例不稳定型心绞痛患者,随机均分成三组:A组给予常规药物治疗;B组给予常规药物治疗和体外反搏,1h/次,1次/d;C组在B组治疗方案的基础上给予丹红注射液40ml+生理盐水250ml或5%葡萄糖250ml静脉滴注,1次/d;12d为一疗程。一疗程后观察三组患者治疗效果、半年内心绞痛再次发作情况及急性心肌梗死(AMI)发生情况。结果:与A组比较,B组和C组患者治疗总有效率显著升高(79.31%比87.72%比96.61%),发作次数[(4.18±1.01)次/周比(2.27±0.96)次/周比(1.25±0.42)次/周]和持续时间[(3.42±0.76)min/次比(2.36±0.87)min/次比(1.15±0.63)min/次]显著减少,半年后心血管事件发生率显著降低(32.76%比22.81%比11.86%),且C组的心绞痛发作次数和持续时间显著少于B组,P<0.01。结论:体外反搏对不稳定型心绞痛患者疗效显著,与丹红注射液联合应用,有协同作用。Objective：To observe the therapeutic effect of external counterpulsation （ECP） combined Danhong injection on patients with unstable angina pectoris （UAP）.Methods：A total of 183 UAP patients were randomly and equally divided into group A （received routine medication）,group B （received routine medication and ECP,1h/time,once/d） and group C （received intravenous drip of 40ml Danhong injection ＋ 250ml normal saline or 5% glucose,once/d based on treatment plan of group B）,and 12d was regard as one course of treatment.Therapeutic effect,recurrence of angina pectoris and incidence of acute myocardial infarction （AMI） within six months were observed in three groups after one course of treatment.Results：Compared with group A after treatment,there was significant increase in total effective rate （79.31% vs.87.72% vs.96.61%）,significant decrease in attack frequency [（4.18 ± 1.01） times/week vs.（2.27± 0.96） times/week vs.（1.25 ± 0.42） times/week],duration [（3.42 ± 0.76） min/time vs.（2.36 ± 0.87） min/time vs.（1.15 ± 0.63） min/time] and incidence rate of cardiovascular events after six months （32.76% vs.22.81% vs.11.86%） in group B and group C,and attack frequency and duration of angina pectoris in group C were significantly lower than those of group B,P〈0.01.Conclusion：External counterpulsation possesses significant therapeutic effect on patients with unstable angina pectoris,and it has synergistic effect when combined with Danhong injection.

关 键 词：反搏动术 心绞痛 不稳定型 治疗结果 

分 类 号：R541.4[医药卫生—心血管疾病]