1型糖尿病患者伴发贫血的特征及危险因素分析  

Characteristics and associated factors in type 1 diabetic patients with anemia

作　　者：陈晔[1] 陈芳芳[2] 王坚[1] 

机构地区：[1]南京军区南京总医院内分泌科,江苏南京210002 [2]南京军区南京总医院中心实验科,江苏南京210002

出　　处：《东南国防医药》2014年第1期37-39,共3页Military Medical Journal of Southeast China

摘　　要：目的研究分析1型糖尿病患者并发贫血的发生率、特点和危险因素。方法分别对入选患者临床和实验室指标进行分析。结果 1型糖尿病94例中,27.6%的患者伴有贫血。病程≥3年以上的患者血红蛋白(Hb)、肌酐(Cr)、糖化血红蛋白(HbA1c)、24 h尿微量白蛋白(24 hUMA)水平显著高于病程<3年的患者,贫血的1型糖尿病患者Hb和Cr呈负相关,相关系数(r)为-0.400(P<0.05),Hb与肾小球滤过率(eGFR)呈正相关,r为0.551(P<0.01)。结论 1型糖尿病患者中贫血的发生率较高,并且与Cr和eGFR密切相关。Objective To investigate the prevalence,characteristics and associated factors of anemia in patients with type 1 diabetes. Methods An analysis of the clinical and laboratory data of type 1 diabetic patients with or without anemia was conducted. Results In 94 cases ,27.6% patients with type 1 diabetes had anemia. The levels of hemoglobin, creatinine, glycosylate hemoglobin, and 24-hour urinary microalbumin were much higher in patients with duration more than or equal to 3 years than that of in patients with duration less than 3 years. The level of hemoglobin was negatively correlated with creatinine and positively correlated with eGFR in type 1 diabetic patients with anemia. Conclusion Anemia is a prevalent finding in type 1 diabetic patients, which is closely associated with Cr and eGFR.

关 键 词：1型糖尿病 贫血 糖尿病肾病 

分 类 号：R587.1[医药卫生—内分泌] R556[医药卫生—内科学]