夏枯草注射液治疗肺癌胸水的临床和实验研究  

Clinical and Experimental Observations of Hydrothorax in Lung Cancer Cases Treated with Closed Drainage and Injection of Selfheal Spike Injection

作　　者：周荣耀[1] 徐中伟[1] 倪爱娣[1] 吴丽英[1] 曹妹芳[1] 冯铮[1] 

机构地区：[1]上海中医药大学附属曙光医院,上海200021

出　　处：《浙江中西医结合杂志》2001年第1期5-8,共4页Zhejiang Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的 :观察夏枯草注射液治疗支气管肺癌胸水的疗效 ,并试图通过动物实验探讨其机理。方法 :178例支气管肺癌伴中等或大量胸水的住院病人 ,均附有病理学或细胞学诊断 ,随机分为夏枯草注射液组 ,榄香烯组和化疗组 ,采用导管导丝操作法 ,细管闭塞引流 ,和胸腔内注射药物治疗。 2通过兔胸腔积液造模 ,胸腔内注射药物后观察胸膜病理变化。结果 :夏枯草注射液组和榄香烯组之间疗效无显著性差异 ,均优于化疗组 ,P<0 .0 1,夏枯草注射液组副作用小于榄香烯和化疗组。动物实验提示夏枯草注射液和榄香烯组的胸膜反应优于对照组。结论 :夏枯草注射液在治疗支气管肺癌胸水方面有较好的疗效且毒副反应极小。Objective:To observe the therapeutic efficacy of selfheal spike injection in treating hydrothorax of bronchopulmonary carcinoma and explore the mechanism through animal experiments.Methods:78 bronchopulmonary carcinoma cases were divided at random into three groups:selfheal spike,elemene and chemotherapy group and treated accordingly so as to observe the pathological changes of the pleura. Results: The therapeutic efficacy of both selfheal spike and elemence was better that of the chemotherapy ( P<0.01 ).No difference was observed between the selfheal spike efficacy and elemence efficacy.The side effect of selfheal spike group was smaller than that of the elemence and chemotherapy groups.Animal experiment showed that the pleural reaction of selfheal spike group was better that of the elemence and chemotherapy groups.Conclusions:Selfheal spike injection was effective in treating hydrothorax with bronchopulmonary carcinoma with less side effects and its mechanism remained to be further studied.

关 键 词：夏枯草注射液 支气管肺癌 胸水 中医药疗法 

分 类 号：R273[医药卫生—中西医结合]