缩宫素引产期间应用间苯三酚的效果观察  

Clinical analysis of phloroglucinol applied to labor induced by oxytocin

作　　者：王雅慧[1] 马艳芬[1] 王秀芳[1] 胡美丽[1] 

机构地区：[1]河北省保定市妇幼保健院产三科,071000

出　　处：《武警医学》2014年第1期51-52,55,共3页Medical Journal of the Chinese People's Armed Police Force

摘　　要：目的观察间苯三酚在缩宫素引产期间的应用效果。方法选择因胎膜早破、延期妊娠、羊水过少进行缩宫素引产的150例孕妇。随机分成实验组和对照组,实验组每日静脉滴注间苯三酚80 mg,至宫口开至3 cm再次静脉滴注间苯三酚80 mg;对照组单纯使用缩宫素静脉滴注。记录实验组和对照组孕妇分娩结局、应用缩宫素素至临产时间、潜伏期及活跃期时间、产后2 h出血量。结果与对照组相比,实验组阴道分娩成功率增高,应用药物至临产的时间缩短,潜伏期和活跃期均缩短,差异具有统计学意义(P<0.05)。第二产程两组无明显差异。实验组与对照组比较,明显减轻产妇对疼痛的耐受情况(P<0.01);但产后2 h出血量比较,差异无统计学意义。结论间苯三酚能加速宫颈口扩张,促进宫颈成熟,缩短产程,降低剖宫产率,减轻痛苦,且对母婴无明显不良影响。Objective To study the results of phloroglucinol applied to the labor induced by oxytocin. Methods 150 preg- nant women were recruited in Baoding Maternal and Child Health Hospital during 2012-2013, who underwent oxytocin induced labor because of premature rupture of membranes, delayed pregnancy, oligohydramnios. They were randomly divided into study group and control group. The study group received intravenous oxytocin daily and phloroglucinol 80 mg, and intravenous phloroglueinol 80 mg a- gain in dilatation of the cervix to 3 cm. The control group was treated by intravenous infllsion of oxytocin. For the study group and the control group, the birth outcomes, application of oxytoein to labor time, latency and time of active period, and 2 h post-partum bleed- ing were recorded. Results Compared with the control group, the success rate of vaginal birth increased using drugs to reduce the time in labor in the study group （ P 〈 0.05 ）. The study group had shortened latency and active period, with statistically significant difference. The second stage had no significant difference between the two groups. The study group, compared with the control group, had significantly reduced maternal tolerance to pain conditions （P 〈 0.01 ） , 2 h postpartum hemorrhage was not significantly different. Conclusions Phloroglucinol accelerates the maternal cervix dilatation and cervical ripening, shortens labor, reduces the cesarean sec- tion rate, reduce maternal pain, and without significant adverse effects on mothers and children.

关 键 词：间苯三酚 缩宫素 潜伏期 活跃期 宫颈扩张 

分 类 号：R714[医药卫生—妇产科学]