基本药物制度对基层医疗卫生机构抗生素使用的影响  

The Impact of the National Essential Medicines Policy on the Rational Use of Antibiotics in Primary Health Facilities in China

作　　者：杨春艳[1,2] 杨诗汝[2] 杨廉平[2] 张新平[2] 

机构地区：[1]湖北科技学院基础医学院,湖北咸宁437100 [2]华中科技大学同济医学院医药卫生管理学院

出　　处：《中国卫生事业管理》2014年第2期109-112,共4页Chinese Health Service Management

基　　金：国家自然科学基金项目"基于高透明导向的基层医疗卫生机构基本药物使用监管回归模型研究"(编号:71173082);中央高校基本科研业务费资助;湖北省人文社科重点研究基地--农村健康服务研究中心科研经费资助项目"湖北省基本药物制度监测与评价研究"(编号:2012WJD006)

摘　　要：目的:研究基本药物制度对基层医疗卫生机构抗生素使用的影响。方法:调查东、中、西部6省120家基层医疗卫生机构住院病人和门诊处方,比较基本制度实施前后抗生素使用的变化。结果:实施基本药物制度后,东、中、西部住院病人使用抗生素比例分别下降了6.94%、6.75%和7.71%,抗生素联用处方比例分别下降了5.70%、2.80%和4.90%,中部下降幅度最小;不同地区抗生素使用现状有明显差异,中部抗生素联用比例最高,西部住院病人使用抗生素比例最高。结论:实施基本药物制度促进了抗生素的合理使用,但影响效果存在地区差异,且基层医疗机构仍存在抗生素过度使用。Objective The purpose of this study is to investigate the impact of NEMP on the rational antibiotic use. Methods Pre- and post-intervention comparisons were designed. Totally 120 primary health facilities from six provinces were investigated. Results Findings showed that after the NEMP the antibiotic uses deceased significantly, and the intervention effect was different a- mong regions. In eastern,central, and western regions, the percentage of hospitalizations with antibiotics was reduced by 6.94%, 6.75 %, and 7.71% （p 〈 0.05）, and the percentage of prescriptions with two or more antibiotics was reduced by 5.70% ,2. 80%, and 4.90% （p 〈 0.05）. The current situation of antibiotic use in eastern, central, and western regions was different. Con- clusion The NEMP was effective in the improvement of rational antibiotic use in Chinese primary health facility, and the effect was different in different regions. However,the current situation of antibiotic use was still serious.

关 键 词：国家基本药物制度 基层医疗卫生机构 抗生素使用 

分 类 号：R96[医药卫生—药理学]