血管新生与冠心病治疗性血管生成  

Angiogenesis and Therapeutic Angiogenesis of Coronary Heart Disease

作　　者：张少言[1] 林赟霄 陈浩[1] 王佑华[1] 

机构地区：[1]上海中医药大学附属龙华医院,上海200032

出　　处：《心血管病学进展》2014年第1期55-59,共5页Advances in Cardiovascular Diseases

基　　金：国家自然科学基金(81328025);国家中医药行业科研专项(201007003-4);上海市自然科学基金项目(12ZR1432200);山东中医药大学附属医院国家中医临床研究基地业务建设科研专项(JDZX2012114)

摘　　要：继冠状动脉再通术后,治疗性血管新生成为冠心病基础与临床研究的热点,但血管新生的影响因素复杂,治疗性血管新生所得到的临床试验结果也不尽一致。现对此做一综述,结合血管新生的影响因素,分析了一些增强血管新生疗效的方法和降低疗效的可能原因,总结了冠心病治疗性血管生成临床研究进展,以期有利于冠心病治疗性血管新生成基础与临床研究。Following the coronary recanalization surgery, therapeutic angiogenesis is becoming a hot spot to the basic and clinical re search of the coronary heart disease. The angiogenesis factors are complex, so the clinical trial results obtained by therapeutic angiogenesis are not the same. In order to help the basic and clinical angiogenesis research of coronary heart disease, this article combined with angiogenesis factors analyzes a number of methods for enhancing angiogenesis effects and the possible reasons of reducing the efficacy and sums up the clinical research of the coronary therapeutic angiogenesis.

关 键 词：血管新生 治疗性 血管生成 

分 类 号：R541.4[医药卫生—心血管疾病]