中性粒细胞和淋巴细胞比率与心血管疾病的关系  

The Relationship of Neutrophil to Lymphocyte and Cardiovascular Diseases

作　　者：李文华[1] 潘薇[1] 

机构地区：[1]哈尔滨医科大学附属第一医院心内科,黑龙江哈尔滨150001

出　　处：《心血管病学进展》2014年第1期67-71,共5页Advances in Cardiovascular Diseases

摘　　要：炎症标志物在心血管疾病中的作用已被广泛研究,研究显示各种炎症标志物与心血管疾病之间具有一致性。中性粒细胞和淋巴细胞比率是最近新增加的一种炎性标志物,是一种价格低廉、容易获得的炎症标志物。在传统的危险因素的基础上,中性粒细胞和淋巴细胞比率有助于心血管疾病患者的危险分层。它与动脉硬化和钙化斑块严重程度显著相关。中性粒细胞和淋巴细胞比率可作为判断稳定型冠状动脉疾病预后的独立指标,并且可预测急性冠状动脉综合征患者的短期及长期病死率。The role of inflammatory markers in cardiovascular diseases has been studied extensively and a consistent relationship be tween various inflammatory markers and cardiovascular diseases has been established in the past. Neutrophil to lymphocyte ratio （NLR） is a new addition to the long list of these inflammatory markers. NLR, which is calculated from complete blood count with differential, is an inex pensive, easy to obtain, widely available marker of inflammation, which can aid in the risk stratification of patients with various cardiovascu lar diseases in addition to the traditionally used markers. It has been associated with arterial stiffness and high coronary calcium score, which are significant markers of cardiovascular disease. NLR is reported as an independent predictor of outcome in stable coronary artery disease, as well as a predictor of short and long-term mortality in patients with acute coronary syndrome.

关 键 词：炎症 中性粒细胞和淋巴细胞比率 心血管疾病 

分 类 号：R54[医药卫生—心血管疾病]