艾司洛尔静脉注射治疗心室电风暴26例  

Intravenous Esmolol in Treatment of 26 Patients with Ventricular Electrical Storm

作　　者：丁超[1] 郭洁[1] 王冬梅[1] 高树军 于敏[1] 赵玉英[1] 

机构地区：[1]解放军白求恩国际和平医院心血管内科,石家庄050082 [2]空军石家庄西三庄干休所,石家庄050081

出　　处：《解放军医药杂志》2014年第1期58-60,共3页Medical & Pharmaceutical Journal of Chinese People’s Liberation Army

基　　金：河北省科技支撑计划项目课题(11276124D)

摘　　要：目的 观察艾司洛尔静脉注射治疗心室电风暴的临床疗效和安全性.方法 2010年6月-2013年2月收治心室电风暴26例,给予艾司洛尔负荷量0.5 mg/kg静脉注射,后以维持量0.05 mg/（kg·min）静脉滴注36~72 h,观察临床疗效并评价其安全性.结果 本组中24例室性心动过速和室颤得到有效控制,控制成功率为92.3%.其中出现严重窦性心动过缓和血压下降各3例,给予相应处理后心率和血压均恢复正常.治疗72 h内有2例反复发生室颤,死亡.结论 应用艾司洛尔静脉注射治疗心室电风暴安全、有效.Objective To observe the clinical efficacy and safety of intravenous Esmolol in treatment of ventricular electrical storm. Methods A total of 26 patients admitted for ventricular electrical storm during June 2010 and February 2013 were intravenously injected with loading dose of 0. 5 mg/kg Esmolol injection, and then were given 0.05 mg/ （kg · min） of maintenance dose within 36 - 72 hours. The clinical efficacy was observed, and safety was evaluated. Results The symptoms of ventricular tachycardia and ventricular fibrillation in the 24 patients were effectively controlled, and the controlling success rate was 92.3%. Three patients with severe sinus bradycardia and three patients with decreased blood pressure recovered after corresponding treatment. Two patients died of repeated ventricular fibrillation within 72 hours of treatment. Conclusion Intravenous Esmolol in treatment of ventricular electrical storm is effective and safe.

关 键 词：艾司洛尔 心律失常 心动过速 室性 心室颤动 

分 类 号：R541.7[医药卫生—心血管疾病] R972.2[医药卫生—内科学]