基于19877例文献病例的血脂异常证候要素及靶位研究  

Study on the dyslipidemia,s syndrome elements and the targets distribution based on the 19 877 literature cases

作　　者：高嘉良[1] 何庆勇[1] 

机构地区：[1]中国中医科学院广安门医院,北京100053

出　　处：《中华中医药杂志》2014年第2期605-607,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金项目(No.81202803)~~

摘　　要：目的:探讨血脂异常证候、证候要素及靶位分布规律。方法:检索知网数据库(C N K I)2002年1月至2012年12月的全部期刊,从符合研究标准的137篇文献的19 877例中提取证候要素,对其进行归类合并,总结证候要素及靶位。结果:19 877例文献病例中共有证候要素11个,主要为痰浊9 571例(48.15%),血瘀7 890例(39.69%),气虚3 634例(18.28%);其靶位共有7个,病位在脾17 308例(87.08%),肝16 578例(83.40%),肾7 084(36.64%);共有证型14个,痰浊中阻证5 084例(25.58%),痰瘀互结证4 605例(23.17%),气滞血瘀证3 288例(16.54%)。结论:痰浊、血瘀是血脂异常较为重要的证候要素,其病位主要涉及脾,其次为肝、肾;其核心病机是脾虚或脾气滞而致痰瘀互结,在治疗上应以运脾化浊为主,运脾方面包括补脾虚、理脾气滞,化浊方面包括化痰浊和化瘀血。Objective： To investigate the dyslipidemia syndromes, the syndrome elements and the distribution of dyslipidemia＇s targets. Methods： All the periodicals were retrieved from CNKI between January 2002 and December 2012. There were 19 877 literature cases met the study criteria, which could be classified and summarized the syndrome elements and the targets distribution. Results： 19 877 cases literature patients had 11 syndrome elements, mainly for the phlegm turbidity 9 571 cases （48.15%）, blood stasis 7 890 cases （39.69%）, deficiency of qi 3 634 cases （18.28%）. There were seven targets for the dyslipedemia, including in spleen 17 308 cases （87.08%）, liver 16 578 cases （83.40%）, renal 7 084 cases （36.64%）. 14 common syndromes had something to do with the dyslipedemia, mainly for phlegm turbidity of resistance syndrome 5 084 cases （25.58%）, phlegm and blood stasis by each other 4 605 cases （23.17%）, and qi stagnation and blood stasis syndrome 3 288 cases （16.54%）. Conclusion： The phlegm turbidity and blood stasis are important syndrome elements of dyslipidemia, which mainly involves in spleen, liver and kidney. The core mechanism of dyslipidemia is phlegm and blood stasis, which is caused by spleen deficient or the block of spleen＇s qi. So the treatment should be paid enough attentions in two parts, which include yun spleen and reducing the turbidity.

关 键 词：血脂异常 证候要素 靶位 分布规律 

分 类 号：R259[医药卫生—中西医结合]