铁核结构对马脾铁蛋白释放铁动力学的影响  

Effect Structure of Iron Core on Kinetics of Iron Release from Horse Spleen Ferritin

作　　者：黄河清[1] 林庆梅[2] 肖志群[1] 陈晶[1] 曾骥[1] 童丽[1] 

机构地区：[1]厦门大学生物学系 [2]厦门大学环境科学研究中心,厦门361005

出　　处：《动物学杂志》2001年第1期18-22,共5页Chinese Journal of Zoology

基　　金：国家自然科学基金! (No.49876 0 2 7) ;教育部高等学校骨干教师资助计划及固体表面物理化学国家重点实验室基金

摘　　要：建立H+参与马脾铁蛋白释放铁的动力学方程。H+以 1 / 2级反应方式参与铁蛋白释放铁核表层的铁。在酸性介质 ( pH 6 5)中 ,铁蛋白释放铁的总平均速率 ( 332Fe3+/HSF·min)比在碱性介质 ( pH8 0 )中释放铁的总平均速率 ( 73Fe3+/HSF·min)高 4 6倍。铁蛋白的铁核结构和外加的磷酸盐均能影响该蛋白释放铁的速率 ,但并不改变其反应级数。A Kinetic equation of iron release with H + existing was established from horse spleen ferritin. H + as a form of half\|order reaction took part in the reaction that the ferritin released it on the surface of iron core. Average rate of iron release (332 Fe 3+ /HSF·min) in the acid\|medium (pH 6 5) was higher 4 6 times than that (73 Fe 3+ /HSF·min) in basic\|medium (pH 8 0). The structure of iron core from horse spleen ferritin and the extra phosphate had an effect upon the rate of iron release, but the reaction order was not changed.

关 键 词：马脾铁蛋白 反应级数 铁核结构 动力学方程 磷酸盐 释放 铁 

分 类 号：Q617[生物学—生物物理学]