血清CRP与hs-CRP检测值比较与相关性分析  

Comparison and Correlation Analysis of Detected-values for CRP and hs-CRP in Sera

作　　者：华关民[1] 唐荣德[1] 梁剑宁[1] 陈敏[1] 

机构地区：[1]广东省江门市新会区中医院,广东江门529100

出　　处：《中国医学创新》2014年第3期32-34,共3页Medical Innovation of China

摘　　要：目的:探讨血清CRP和hs-CRP检测的临床应用价值。方法:收集住院患者入院第1次检测的CRP和hs-CRP资料,然后以hs-CRP为标准按检测值高低分为四组,进行其检测值比较与相关性分析。结果:组内比较,正常范围组两项指标组内比较差异有统计学意义(P<0.01)。随机病例数是正常范围组>轻度升高组>中度升高组>重度升高组,各组CRP和hs-CRP检测值均有较好的相关性(均为P<0.01),组间比较在轻度升高组和重度升高组与正常范围组比较差异均有统计学意义(P<0.01,P<0.05),但轻度、中度、重度升高组之间比较差异均无统计学意义(P>0.05)。结论:低限时CRP和hs-CRP的相关性相对较差是由于CRP下限检出率很高所致。首诊时最好作hsCRP检测,以便CRP低限能够检出,使之用作CHD等多种疾病的辅助诊断。Objective：To explore the values of clinical application for the detections of CRP and hs-CRP in sera.Method：First tested data of CRP and hs-CRP were collected on admission for hospitalized patients.They were divided into 4 groups according to the difference in degree of hs-CRP. The detected-values and correlation analysis were compared.Result：The normal group had very obviously difference for comparison in group of 2 indexes （Pmildly elevated group〉moderately elevated group〉severe elevated group.The detected-values of CRP and hs-CRP in each groups all had better correlation（all P0.05）.Conclusion：Lower limit of CRP and the correlation of the hs-CRP is relatively poor due to lower limit CRP detection rate is very high.When the first option is best for the hs-CRP detection,so that CRP low limit of detection,make it as auxiliary diagnosis for such as CHD etc multiple diseases.

关 键 词：C反应蛋白 高敏感C反应蛋白 检测值 比较 相关性分析 

分 类 号：R446.6[医药卫生—诊断学]